Interfacial Cholesterol Binding Sites on GPCRs
GPCRs Class A [Part Two]
[With residue numbers in the Ballesteros-Weinstein numbering system; Units of E, kcals/mol with molar concentration units]
PDB | E | Local Residues |
Cannabinoid CB1 receptor | ||
Cannabinoid CB1, inactive, Human 5tgz | ||
5tgz_EC | -13.3 | I353[6.45], I354[6.46], P358[6.50], A361[6.53], Y365[6.57], N372[7.28], L374[7.30], I375[7.31], V378[7.34] |
-13.0 | A120[1.36], V121[1.37], L124[1.40], T125[1.41], F174[2.61], H178[2.65], V179[2.66], H181 | |
-12.1 | L287[5.51], V291[5.55], I353[6.45], G357[6.49], L360[6.52], A361[6.53], V364[6.56], Y365[6.57] | |
5tgz_IC | -15.4 | L142[1.58], R148, H154[2.41], V161[2.48], L165[2.52], R230[4.39], V234[4.43], C238[4.47] |
-13.4 | F208[3.44], L209[3.45], I212[3.48], I227, K232[4.41], A236[4.45], L239[4.48], I243[4.52], L286[5.50] | |
Cannabinoid CB1, inactive, Human 5u09 | ||
5u09_EC | -12.9 | T274[5.38], M277[5.41], F278[5.42], G281[5.45], V282[5.46], V285[5.49], F289[5.53], F368[6.60] |
-12.7 | I354[6.46], P358[6.50], A361[6.53], I362[6.54], Y365[6.57], K370, N372[7.28], I375[7.31], V378[7.34] | |
-12.7 | L138[1.54], V161[2.48], L164[2.51], L165[2.52], V168[2.55], I169[2.56], Y172[2.59], R182, V188[3.24], F191[3.27], K192[3.28] | |
-12.6 | L124[1.40], T125[1.41], T128[1.44], F129[1.45], L132[1.48], I175[2.62], V179[2.66], F180 | |
-12.6 | L287[5.51], L288[5.52], V291[5.55], I353[6.45], A361[6.53], V364[6.56], Y365[6.57], F368[6.60], G369[6.61] | |
5u09_IC | -15.7 | I141[1.57], L142[1.58], L147, R148, Y153[2.40], H154[2.41], I156[2.43], G157[2.44], S158[2.45], V161[2.48] |
-12.7 | F208[3.44], L209[3.45], K232[4.41], A236[4.45], L239[4.48], I243[4.52], I247[4.56], V282[5.46] | |
Cannabinoid CB1, active intermediate, with cholesterol, Human 5xr8 | ||
5xr8_EC | -13.7 | L135[1.51], L164[2.51], L165[2.52], V168[2.55], I169[2.56], Y172[2.59], R182, K192[3.28] |
-12.9 | L124[1.40], T128[1.44], L132[1.48], V171[2.58], Y172[2.59], I175[2.62], D176[2.63], F180 | |
-12.9 | L117[1.33], A120[1.36], V121[1.37], L124[1.40], T125[1.41], T128[1.44], F129[1.45], L132[1.48], V179[2.66] | |
5xr8_IC | -15.2 | I141[1.57], Y153[2.40], H154[2.41], G157[2.44], S158[2.45], V161[2.48], L165[2.52], W241[4.50], I245[4.54] |
-13.1 | K343[6.35], L347[6.39], V351[6.43], I354[6.46], V392[7.48], I395[7.51], I396[7.52], L399[7.55], R400[7.56] | |
-12.4 | F208[3.44], L209[3.45], I212[3.48], K232[4.41], A236[4.45], I243[4.52], F278[5.42], V282[5.46] | |
-12.8 | F208[3.44], I212[3.48], I216[3.52], I227, G281[5.45], V282[5.46], V285[5.49], F289[5.53] | |
Cannabinoid CB1, active intermediate, with cholesterol, Human 5xra | ||
5xra_EC | -13.7 | L124[1.40], T128[1.44], L132[1.48], V171[2.58], Y172[2.59], I175[2.62], D176[2.63], F180 |
5xra_IC | -15.8 | H154[2.41], G157[2.44], S158[2.45], V161[2.48], L165[2.52], F237[4.46], C238[4.47], W241[4.50], I245[4.54] |
-12.9 | F208[3.44], L209[3.45], K232[4.41], A233[4.42], V235[4.44], A236[4.45], L239[4.48], I243[4.52], F278[5.42], V282[5.46] | |
-12.4 | F208[3.44], I212[3.48], I216[3.52], I227, G281[5.45], V282[5.46], V285[5.49], L286[5.50] | |
-14.2 | I212[3.48], Y215[3.51], I216[3.52], R220[3.56], V285[5.49], L288[5.52], F289[5.53], Y292[5.56] | |
Chemokine CC receptor | ||
Chemokine CC receptor, Type 2, inactive, Human 5t1a | ||
5t1a_EC | -13.1 | L90[2.52], K114[3.26], L115[3.27], G118[3.30], L119[3.31], I122[3.34], W165[4.50], V169[4.54], I176[4.61] |
-13.1 | V167[4.52], F170[4.55], V173[4.58], P174[4.59], I177[4.62], F178[4.63], W198[5.35], F201[5.38] | |
-12.9 | F253[6.45], L254[6.46], T257[6.49], P258[6.50], I261[6.53], V262[6.54], L265[6.57], L283[7.30], A286[7.33] | |
-12.8 | S50[1.40], F53[1.43], I54[1.44], F57[1.47], V58[1.48], P96[2.58], A99[2.61], H100[2.62], A103[2.65] | |
-12.2 | I40[1.30], L44[1.34], L48[1.38], V289[7.36], T292[7.39], L293[7.40], T296[7.43], C299[7.46], I300[7.47] | |
-13.7 | F53[1.43], F57[1.47], M61[1.51], I93[2.55], P96[2.58], L97[2.59], H100[2.62], F108 | |
5t1a_IC | -13.5 | L73, I79[2.41], L82[2.44], N83[2.45], I86[2.48], L90[2.52], L119[3.31], I122[3.34], V158[4.43], V162[4.47], W165[4.50], V169[4.54] |
-12.9 | T247[6.39], V251[6.43], L254[6.46], F255[6.47], T296[7.43], I300[7.47], I304[7.51], F307[7.54], V308[7.55] | |
-12.4 | I132[3.44], L133[3.45], I136[3.48], F156[4.41], V167[4.52], M205[5.42], L209[5.46], L213[5.50] | |
Chemokine CC receptor, Type 5, inactive, Human 4mbs | ||
4mbs_EC | -14.1 | Q102[3.26], L103[3.27], G106[3.30], I110[3.34], V150[4.47], W153[4.50], V154[4.51], V157[4.54], I164[4.61] |
-12.4 | V155[4.52], F158[4.55], A159[4.56], L161[4.58], P162[4.59], W190[5.35], F193[5.38], K197[5.42], L201[5.46] | |
-12.2 | F245[6.45], L246[6.46], A249[6.49], P250[6.50], I253[6.53], V254[6.54], L257[6.57], R274[7.29] | |
-12.2 | L32[1.34], L36[1.38], F247[6.47], V281[7.36], T284[7.39], L285[7.40], T288[7.43], I292[7.47], I295[7.50] | |
4mbs_IC | -12.8 | I124[3.48], Y127[3.51], I200[5.45], V204[5.49], L205[5.50], L208[5.53], V209[5.54], I212[5.57], C213[5.58] |
-12.4 | L61, I67[2.41], N71[2.45], F78[2.52], V146[4.43], V150[4.47], W153[4.50], V157[4.54] | |
-12.4 | R235[6.35], T239[6.39], V243[6.43], F247[6.47], I292[7.47], I295[7.50], I296[7.51], F299[7.54], V300[7.55] | |
-13.5 | M64[2.38], I120[3.44], L121[3.45], I124[3.48], L128[3.52], F144[4.41], T148[4.45], L201[5.46], L205[5.50] | |
-12.6 | F45[1.47], V46[1.48], M49[1.51], L50[1.52], L53[1.55], I54[1.56], Y307[8.53], F311[8.57] | |
Chemokine CC receptor, Type 9, inactive, with cholesterol, Human 5lwe | ||
5lwe_EC | -13.6 | R44[1.28], F46[1.30], A47[1.31], F50[1.34], L51[1.35], I297[7.32], Q300[7.35], V301[7.36], A304[7.39], I305[7.40] |
-12.6 | L175[4.52], A178[4.55], L179[4.56], I181[4.58], P182[4.59], L185[4.62], Y186[4.63], V214[5.39], L217[5.42], K218[5.43], L221[5.46] | |
-12.4 | F117[3.23], K120[3.26], V121[3.27], S124[3.30], M125[3.31], W173[4.50], V174[4.51], I184[4.61] | |
5lwe_IC | -13.6 | W74[1.58], M85[2.41], L88[2.44], N89[2.45], I92[2.48], L96[2.52], K166[4.43], F170[4.47], W173[4.50] |
-12.9 | K254[6.35], T258[6.39], T261[6.42], V262[6.43], L265[6.46], I305[7.40], F308[7.43], L312[7.47], L316[7.51] | |
-12.4 | F50[1.34], L54[1.38], L57[1.41], F308[7.43], L312[7.47], V315[7.50], L316[7.51], F319[7.54] | |
Chemokine CXC receptor | ||
Chemokine CXC Receptor Type 4, inactive, Human 3odu | ||
3odu_EC | -12.6 | L167[4.56], L194[5.34], V197[5.37], V198[5.38], F201[5.41], Q202[5.42], M205[5.45], V206[5.46] |
-12.6 | P163[4.52], L166[4.55], L167[4.56], I169[4.58], P170[4.59], I173[4.62], F174[4.63], W195[5.35] | |
-12.1 | L208[5.48], F249[6.45], L253[6.49], Y256[6.52], I257[6.53], S260[6.56], I261[6.57], F264[6.60], I270 | |
-12.1 | K38[1.32], I39[1.33], P42[1.36], T43[1.37], S46[1.40], I47[1.41], L50[1.44], V99[2.65] | |
-12.9 | V197[5.37], Q200[5.40], F201[5.41], I204[5.44], I209[5.49], S263[6.59], L266[6.62], L267[6.63] | |
3odu_IC | -14.2 | H79[2.45], V82[2.48], L86[2.52], A111[3.27], V114[3.30], I115[3.31], Y157[4.46], W161[4.50], L165[4.54] |
-13.3 | I60[1.54], Y65[1.59], V82[2.48], L85[2.51], L86[2.52], I89[2.55], T90[2.56], F93[2.59], I115[3.31] | |
-13.0 | I47[1.41], T51[1.45], G55[1.49], L58[1.52], F293[7.43], C296[7.46], P299[7.49], I300[7.50], A303[7.53], F304[7.54] | |
-12.7 | W125[3.41], F129[3.45], L132[3.48], L151[4.40], V155[4.44], G159[4.48], P163[4.52], L167[4.56], Q202[5.42], V206[5.46], L210[5.50] | |
-12.6 | A247[6.43], A250[6.46], C251[6.47], P254[6.50], L290[7.40], L297[7.47], I300[7.50], L301[7.51], F304[7.54] | |
-12.3 | I215[5.55], L216[5.56], Y219[5.59], V242[6.38], I245[6.41], L246[6.42], F249[6.45], L253[6.49], Y256[6.52] | |
Chemokine CXC Receptor Type 4, inactive, Human 3oe0 | ||
3oe0_EC | -13.0 | K38[1.32], I39[1.33], P42[1.36], T43[1.37], S46[1.40], I47[1.41], L50[1.44], V99[2.65] |
-12.4 | L208[5.48], L253[6.49], I257[6.53], S260[6.56], I261[6.57], F264[6.60], I270, F276[7.26] | |
-12.8 | P42[1.36], S46[1.40], F49[1.43], L50[1.44], I53[1.47], P92[2.58], A95[2.61], V96[2.62], V99[2.65] | |
-12.3 | P163[4.52], L166[4.55], L167[4.56], I169[4.58], P170[4.59], I173[4.62], W195[5.35], F199[5.39], Q202[5.42] | |
3oe0_IC | -13.1 | G64[1.58], L78[2.44], H79[2.45], V82[2.48], L86[2.52], V114[3.30], V118[3.34], Y157[4.46], W161[4.50], L165[4.54] |
-13.0 | W125[3.41], F129[3.45], L132[3.48], L151[4.40], V155[4.44], G159[4.48], P163[4.52], L167[4.56], Q202[5.42], V206[5.46], L210[5.50] | |
Chemokine CXC Receptor Type 4, inactive, Human 3oe6 | ||
3oe6_EC | -15.6 | P254[6.50], I257[6.53], G258[6.54], I261[6.57], F276[7.26], T279[7.29], V280[7.30], W283[7.33], T287[7.37] |
-13.0 | P163[4.52], L166[4.55], L167[4.56], I169[4.58], P170[4.59], I173[4.62], F174[4.63], W195[5.35], F199[5.39], Q202[5.42], V206[5.46] | |
-12.5 | F49[1.43], I53[1.47], I89[2.55], P92[2.58], F93[2.59], V96[2.62], Y103, F104 | |
-12.0 | K38[1.32], I39[1.33], P42[1.36], T43[1.37], S46[1.40], I47[1.41], L50[1.44], V99[2.65] | |
3oe6_IC | -13.7 | L216[5.56], Y219[5.59], I223[5.63], V242[6.38], I245[6.41], L246[6.42], F249[6.45], L253[6.49], Y256[6.52] |
-12.9 | W125[3.41], F129[3.45], L132[3.48], L151[4.40], V155[4.44], V158[4.47], G159[4.48], P163[4.52], L167[4.56], V206[5.46] | |
-12.8 | R70, L78[2.44], H79[2.45], V82[2.48], L86[2.52], V114[3.30], I115[3.31], V118[3.34], Y157[4.46], W161[4.50], L165[4.54] | |
-12.4 | I243[6.39], A247[6.43], P254[6.50], L290[7.40], F293[7.43], L297[7.47], I300[7.50], L301[7.51] | |
-12.7 | L132[3.48], Y135[3.51], M205[5.45], L210[5.50], I213[5.53], V214[5.54], S217[5.57], I221[5.61] | |
-12.3 | I44[1.38], I47[1.41], I48[1.42], T51[1.45], L290[7.40], F293[7.43], I300[7.50], F304[7.54] | |
Chemokine CXC Receptor Type 4, inactive, Human 3oe8 | ||
3oe8_EC | -13.2 | L208.B[5.48], I209.B[5.49], G212.B[5.52], I213.B[5.53], F249.B[6.45], Y256.B[6.52], I257.B[6.53], S260.B[6.56], I261.B[6.57] |
3oe8_IC | -13.7 | H79.B[2.45], V82.B[2.48], L86.B[2.52], A111.B[3.27], V114.B[3.30], I115.B[3.31], Y157.B[4.46], W161.B[4.50], L165.B[4.54] |
-13.4 | T51.B[1.45], V54.B[1.48], G55.B[1.49], L58.B[1.52], V59.B[1.53], V62.B[1.56], K67.B, P299.B[7.49], I300.B[7.50], Y302.B[7.52], A303.B[7.53] | |
-12.4 | F129.B[3.45], V155.B[4.44], V158.B[4.47], G159.B[4.48], P163.B[4.52], L166.B[4.55], L167.B[4.56], I169.B[4.58], P170.B[4.59], Q202.B[5.42] | |
-12.1 | W125.B[3.41], V155.B[4.44], G159.B[4.48], P163.B[4.52], F201.B[5.41], Q202.B[5.42], V206.B[5.46], L210.B[5.50] | |
Chemokine CXC Receptor Type 4, inactive, Human 3oe9 | ||
3oe9_EC | -12.4 | V196[5.36], V197[5.37], Q200[5.40], F201[5.41], I204[5.44], I209[5.49], I259[6.55], S263[6.59], L266[6.62] |
-12.2 | L253[6.49], P254[6.50], I257[6.53], G258[6.54], I261[6.57], V280[7.30], W283[7.33], T287[7.37] | |
-11.7 | L208[5.48], F249[6.45], L253[6.49], I257[6.53], S260[6.56], I261[6.57], F264[6.60], I270 | |
-11.6 | F40[1.34], A247[6.43], A250[6.46], P254[6.50], K282[7.32], W283[7.33], I286[7.36], L290[7.40] | |
-11.6 | F49[1.43], I53[1.47], L85[2.51], I89[2.55], P92[2.58], F93[2.59], V96[2.62], F104 | |
3oe9_IC | -12.9 | V82[2.48], L86[2.52], F107[3.23], A111[3.27], V114[3.30], Y157[4.46], W161[4.50], L165[4.54], F172[4.61] |
-12.9 | V155[4.44], V158[4.47], G159[4.48], P163[4.52], L167[4.56], P170[4.59], F199[5.39], Q202[5.42], V206[5.46] | |
-12.8 | I243[6.39], A247[6.43], A250[6.46], C251[6.47], L297[7.47], I300[7.50], L301[7.51], A303[7.53] | |
-12.3 | I47[1.41], L50[1.44], T51[1.45], V54[1.48], G55[1.49], L58[1.52], P299[7.49], Y302[7.52] | |
Chemokine CXC Receptor Type 4, inactive, Human 4rws | ||
4rws_EC | -13.2 | P163[4.52], L166[4.55], L167[4.56], I169[4.58], P170[4.59], I173[4.62], W195[5.35], F199[5.39], Q202[5.42], V206[5.46], L210[5.50] |
4rws_IC | -13.2 | I204[5.44], L208[5.48], I209[5.49], G212[5.52], I215[5.55], L216[5.56], Y219[5.59], V242[6.38], I245[6.41], L246[6.42], F249[6.45] |
-13.0 | I47[1.41], L50[1.44], T51[1.45], V54[1.48], G55[1.49], L58[1.52], P299[7.49], I300[7.50], Y302[7.52], A303[7.53] | |
-12.9 | A247[6.43], A250[6.46], C251[6.47], P254[6.50], L290[7.40], F293[7.43], L297[7.47], I300[7.50], L301[7.51], A303[7.53] | |
-12.5 | W125[3.41], F129[3.45], L132[3.48], L151[4.40], V155[4.44], G159[4.48], P163[4.52], L166[4.55], L167[4.56], V206[5.46] | |
-13.9 | I44[1.38], I47[1.41], I48[1.42], T51[1.45], L290[7.40], F293[7.43], I300[7.50], A303[7.53] | |
-13.9 | G64[1.58], Y65[1.59], L78[2.44], V82[2.48], L86[2.52], V118[3.34], Y157[4.46], L165[4.54] | |
Complement C5a receptor | ||
Complement C5a receptor, inactive, Human 5o9h | ||
5o9h_EC | -13.1 | I253[6.46], L256[6.49], P257[6.50], V260[6.53], M264[6.57], T274[7.27], L278[7.31], F288[7.41] |
-13.0 | F48[1.43], V52[1.47], F83[2.51], L87[2.55], P90[2.58], A91[2.59], F104, A108[3.24], L112[3.28] | |
-12.7 | V80[2.48], L84[2.52], S110[3.26], I111[3.27], L115[3.31], L118[3.34], L165[4.54], A172[4.61], L173[4.62] | |
-12.4 | L207[5.43], F211[5.47], L212[5.48], L215[5.51], L256[6.49], V260[6.53], I263[6.56], M264[6.57], F267[6.60] | |
-12.9 | V80[2.48], F83[2.51], L84[2.52], L87[2.55], A107[3.23], A108[3.24], I111[3.27], L112[3.28] | |
-11.7 | L33, I38[1.33], L41[1.36], V42[1.37], A45[1.40], V46[1.41], L49[1.44], F93[2.61], V97[2.65] | |
-11.8 | F48[1.43], L49[1.44], L53[1.48], P90[2.58], F93[2.61], T94[2.62], V97[2.65], Q98[2.66] | |
5o9h_IC | -13.1 | I253[6.46], L256[6.49], P257[6.50], V260[6.53], M264[6.57], T274[7.27], L278[7.31], F288[7.41] |
-13.0 | F48[1.43], V52[1.47], F83[2.51], L87[2.55], P90[2.58], A91[2.59], F104, A108[3.24], L112[3.28] | |
-12.7 | V80[2.48], L84[2.52], S110[3.26], I111[3.27], L115[3.31], L118[3.34], L165[4.54], A172[4.61], L173[4.62] | |
-12.4 | L207[5.43], F211[5.47], L212[5.48], L215[5.51], L256[6.49], V260[6.53], I263[6.56], M264[6.57], F267[6.60] | |
-12.9 | V80[2.48], F83[2.51], L84[2.52], L87[2.55], A107[3.23], A108[3.24], I111[3.27], L112[3.28] | |
-11.7 | L33, I38[1.33], L41[1.36], V42[1.37], A45[1.40], V46[1.41], L49[1.44], F93[2.61], V97[2.65] | |
-11.8 | F48[1.43], L49[1.44], L53[1.48], P90[2.58], F93[2.61], T94[2.62], V97[2.65], Q98[2.66] | |
Complement C5a receptor, inactive, residues renumbered, Human6c1q | ||
6c1q_EC | -13.9 | L163[4.52], L167[4.56], P170[4.59], Y174[4.63], R198[5.34], V202[5.38], V205[5.41], L209[5.45] |
-13.6 | F48[1.43], V52[1.47], F83[2.51], L87[2.55], I91[2.59], F190, A108[3.24], L112[3.28] | |
-12.0 | I253[6.46], L256[6.49], P257[6.50], V260[6.53], T261[6.54], M264[6.57], T274[7.27], L277[7.30], L278[7.31], L281[7.34] | |
-12.0 | F48[1.43], L49[1.44], L53[1.48], P90[2.58], I91[2.59], T94[2.62], Q98[2.66], P189, F190 | |
-11.9 | F83[2.51], L84[2.52], L87[2.55], F190, A107[3.23], A108[3.24], I111[3.27], L112[3.28] | |
-11.8 | L207[5.43], F211[5.47], L212[5.48], L215[5.51], L256[6.49], V260[6.53], I263[6.56], M264[6.57], F267[6.60] | |
-11.6 | V35[1.30], P36[1.31], L39[1.34], I253[6.46], L256[6.49], P257[6.50], L277[7.30], L281[7.34], L284[7.37], F288[7.41] | |
6c1q_IC | -13.9 | L163[4.52], L167[4.56], P170[4.59], Y174[4.63], R198[5.34], V202[5.38], V205[5.41], L209[5.45] |
-13.6 | F48[1.43], V52[1.47], F83[2.51], L87[2.55], I91[2.59], F190, A108[3.24], L112[3.28] | |
-12.0 | I253[6.46], L256[6.49], P257[6.50], V260[6.53], T261[6.54], M264[6.57], T274[7.27], L277[7.30], L278[7.31], L281[7.34] | |
-12.0 | F48[1.43], L49[1.44], L53[1.48], P90[2.58], I91[2.59], T94[2.62], Q98[2.66], P189, F190 | |
-11.9 | F83[2.51], L84[2.52], L87[2.55], F190, A107[3.23], A108[3.24], I111[3.27], L112[3.28] | |
-11.8 | L207[5.43], F211[5.47], L212[5.48], L215[5.51], L256[6.49], V260[6.53], I263[6.56], M264[6.57], F267[6.60] | |
-11.6 | V35[1.30], P36[1.31], L39[1.34], I253[6.46], L256[6.49], P257[6.50], L277[7.30], L281[7.34], L284[7.37], F288[7.41] | |
Complement C5a receptor, inactive, residues renumbered, 6c1r | ||
6c1r_EC | -13.1 | F48[1.43], V52[1.47], F83[2.51], L87[2.55], P90[2.58], I91[2.59], F190, G105[3.21], A108[3.24], L112[3.28] |
-12.7 | R197[5.33], R200[5.36], A201[5.37], I204[5.40], V205[5.41], V208[5.44], L209[5.45], W213[5.49] | |
-12.4 | L207[5.43], F211[5.47], L212[5.48], L215[5.51], L256[6.49], V260[6.53], I263[6.56], M264[6.57], F267[6.60] | |
-12.4 | V80[2.48], F83[2.51], L84[2.52], L87[2.55], A107[3.23], A108[3.24], I111[3.27], L112[3.28], L115[3.31] | |
-12.3 | I253[6.46], L256[6.49], P257[6.50], V260[6.53], T261[6.54], M264[6.57], T274[7.27], L277[7.30], L278[7.31], L281[7.34] | |
-12.2 | V35[1.30], P36[1.31], L39[1.34], I253[6.46], F254[6.47], L277[7.30], L281[7.34], L284[7.37], F288[7.41] | |
-12.1 | F48[1.43], L49[1.44], P90[2.58], I91[2.59], T94[2.62], Q98[2.66], P189, F190 | |
6c1r_IC | -13.1 | F48[1.43], V52[1.47], F83[2.51], L87[2.55], P90[2.58], I91[2.59], F190, G105[3.21], A108[3.24], L112[3.28] |
-12.7 | R197[5.33], R200[5.36], A201[5.37], I204[5.40], V205[5.41], V208[5.44], L209[5.45], W213[5.49] | |
-12.4 | L207[5.43], F211[5.47], L212[5.48], L215[5.51], L256[6.49], V260[6.53], I263[6.56], M264[6.57], F267[6.60] | |
-12.4 | V80[2.48], F83[2.51], L84[2.52], L87[2.55], A107[3.23], A108[3.24], I111[3.27], L112[3.28], L115[3.31] | |
-12.3 | I253[6.46], L256[6.49], P257[6.50], V260[6.53], T261[6.54], M264[6.57], T274[7.27], L277[7.30], L278[7.31], L281[7.34] | |
-12.2 | V35[1.30], P36[1.31], L39[1.34], I253[6.46], F254[6.47], L277[7.30], L281[7.34], L284[7.37], F288[7.41] | |
-12.1 | F48[1.43], L49[1.44], P90[2.58], I91[2.59], T94[2.62], Q98[2.66], P189, F190 | |
Dopamine receptor | ||
Dopamine receptor D2, inactive, Human 6c38 | ||
6c38_EC | -13.7, | L162[4.52], I166[4.56], P169[4.59], L174, N175, N176, Y192[5.41], V196[5.45] |
-12.6, | V190[5.39], V191[5.40], I195[5.44], Y199[5.48], I203[5.52], L206[5.55], I415[7.42], I418[7.45] | |
-12.5, | T42[1.40], I45[1.43], V49[1.47], T85[2.55], P89[2.59], V92[2.62], Y93[2.63], V96[2.66], V97[2.67] | |
-13.0, | F202[5.51], L206[5.55], I404[7.31], L408[7.35], I412[7.39], I415[7.42], L416[7.43], H419[7.46] | |
6c38_IC | -14.6, | Y209[5.58], I210[5.59], I212[5.61], Y213[5.62], A397[6.59], G401, I404[7.31], I405[7.32], L408[7.35], P409[7.36], I412[7.39] |
-14.4, | L82[2.52], L86[2.56], L113[3.31], M116[3.34], M117[3.35], T153[4.43], I156[4.46], S157[4.47], W160[4.50] | |
-12.5, | C126[3.44], I130[3.48], R151[4.41], M155[4.45], I158[4.48], L162[4.52], V196[5.45], V200[5.49] | |
-12.4, | L40[1.38], V47[1.45], F50[1.48], L54[1.52], I445, T448, F458, L462 | |
-12.4, | T42[1.40], I45[1.43], A46[1.44], V49[1.47], F50[1.48], L54[1.52], M57[1.55], I461, L462 | |
Dopamine receptor D3, inactive, Human 3pbl | ||
3pbl_EC | -14.7, | I339[6.45], V340[6.46], L343[6.49], P344[6.50], L347[6.53], T348[6.54], H359, L364[7.34] |
-13.4, | I190[5.40], V194[5.44], Y198[5.48], F201[5.51], G202[5.52], V205[5.55], V350[6.56], H354[6.60] | |
-12.6, | I40[1.43], L41[1.44], V44[1.47], T80[2.55], P84[2.59], V87[2.62], Y88[2.63], V91[2.66] | |
3pbl_IC | -15.0, | Y208[5.58], I211[5.61], Y212[5.62], A332[6.38], L335[6.41], G336[6.42], I339[6.45], V340[6.46], L343[6.49], P344[6.50] |
-13.5, | S35[1.38], A38[1.41], L39[1.42], A42[1.45], F45[1.48], G46[1.49], L49[1.52], W370[7.40], A377[7.47], V381[7.51], T384[7.54], F394[8.54], L398[8.58] | |
-13.2, | Y66[2.41], V69[2.44], S70[2.45], A151[4.43], I154[4.46], T155[4.47], W158[4.50], V159[4.51], F162[4.54] | |
-12.5, | W119[3.41], R149[4.41], L152[4.44], M153[4.45], A156[4.48], L160[4.52], V195[5.45], L199[5.49] | |
-12.4, | I40[1.43], L41[1.44], V44[1.47], F45[1.48], L49[1.52], M52[1.55], I397[8.57], L398[8.58] | |
-12.4, | V44[1.47], G48[1.51], C51[1.54], M52[1.55], L55[1.58], L76[2.51], T80[2.55], L81[2.56] | |
Dopamine receptor D4, inactive, Human 5wiu | ||
5wiu_EC | -14.0, | G40[1.38], L43[1.41], R428[7.33], L429[7.34], S431[7.36], A432[7.37], W435[7.40], V439[7.44] |
-13.1, | V42[1.40], I45[1.43], G46[1.44], L49[1.47], A50[1.48], P89[2.59], L90[2.60], V92[2.62], Y93[2.63] | |
-12.3, | F202[5.48], P206[5.52], L209[5.55], L210[5.56], V412[6.53], I415[6.56], T416[6.57], L419[6.60] | |
-12.5, | F124[3.41], C127[3.44], A128[3.45], T159[4.49], L162[4.52], V166[4.56], Y195[5.41], C199[5.45], L203[5.49] | |
-12.4, | V194[5.40], V198[5.44], F202[5.48], L203[5.49], P206[5.52], L210[5.56], I415[6.56], L419[6.60] | |
5wiu_IC | -14.0, | S71[2.41], V74[2.44], S75[2.45], A78[2.48], L82[2.52], L86[2.56], M114[3.31], M117[3.34], L153[4.43], I156[4.46], W160[4.50] |
-13.5, | R394[6.35], P397[6.38], V398[6.39], G401[6.42], L404[6.45], L405[6.46], T408[6.49], F451[7.56] | |
-13.2, | L209[5.55], Y212[5.58], F216[5.62], P397[6.38], V400[6.41], G401[6.42], L404[6.45], L405[6.46], T408[6.49] | |
-12.9, | C56[1.54], V57[1.55], V59[1.57], A60[1.58], V74[2.44], A78[2.48], L82[2.52], L85[2.55], L86[2.56] | |
Dopamine receptor D4, inactive, Human 5wiv | ||
5wiv_EC | -13.8, | Q33[1.31], A36[1.34], A37[1.35], G40[1.38], R428[7.33], W435[7.40], V439[7.44], L443[7.48] |
-13.4, | V42[1.40], I45[1.43], G46[1.44], L49[1.47], A50[1.48], P89[2.59], L90[2.60], V92[2.62], Y93[2.63] | |
-11.7, | F202[5.48], L209[5.55], L404[6.45], T408[6.49], V412[6.53], I415[6.56], T416[6.57], L419[6.60] | |
5wiv_IC | -13.9, | S71[2.41], V74[2.44], S75[2.45], A78[2.48], L82[2.52], L86[2.56], L153[4.43], I156[4.46] |
-13.1, | L209[5.55], Y212[5.58], W213[5.59], F216[5.62], P397[6.38], G401[6.42], L404[6.45], L405[6.46], T408[6.49], P409[6.50] | |
-13.2, | C56[1.54], V59[1.57], A60[1.58], V74[2.44], L81[2.51], L82[2.52], L85[2.55], L86[2.56] | |
Endothelin ETB receptor | ||
Endothelin ETB receptor, inactive, Human 5glh | ||
5glh_EC | -13.0 | V228[4.52], V231[4.55], L232[4.56], V234[4.58], P235[4.59], I238[4.62], T263[5.28], F265[5.30], M266[5.31] |
-12.1 | E172[3.23], K175[3.26], F179[3.30], V227[4.51], V230[4.54], V231[4.55], V234[4.58], A237[4.61] | |
5glh_IC | -15.3 | L286[5.51], A290[5.55], Y293[5.58], K323[6.35], T324[6.36], F326[6.38], C327[6.39], L330[6.42] |
-13.8 | L190[3.41], A194[3.45], I197[3.48], R201[3.52], E221[4.45], L224[4.48], V228[4.52], L232[4.56] | |
-13.5 | L110[1.41], V113[1.44], L114[1.45], I117[1.48], F397[8.54], K398[8.55], A400[8.57], L401[8.58] | |
-13.1 | F112[1.43], V113[1.44], I116[1.47], I117[1.48], S120[1.51], T121[1.52], Y124[1.55], K128[1.59] | |
-12.8 | I138[2.41], L145[2.48], A219[4.43], I222[4.46], V223[4.47], W226[4.50], V227[4.51], V230[4.54] | |
Endothelin ETB receptor, inactive, Human 5gli | ||
5gli_EC | -12.8 | N104[1.35], D147[2.50], H150[2.53], I155[2.58], N158[2.61], K161[2.64], L162[2.65], Q181[3.32], V185[3.36], T188[3.39], W336[6.48], I372[7.39], A375[7.42], S376[7.43], N378[7.45], S379[7.46] |
-12.1 | I116[1.47], V152[2.55], I153[2.56], P156[2.59], I157[2.60], Y160[2.63], F169, M173[3.24] | |
5gli_IC | -14.0 | I116[1.47], S120[1.51], T121[1.52], Y124[1.55], L148[2.51], V152[2.55], A400[8.57], L401[8.58], C403[8.60] |
-13.4 | A194[3.45], I197[3.48], D198[3.49], R201[3.52], E221[4.45], L224[4.48], V228[4.52], L232[4.56] | |
-13.1 | Y127[1.58], L145[2.48], F179[3.30], V214[4.38], A219[4.43], I222[4.46], V223[4.47], W226[4.50], V230[4.54] | |
-12.3 | F278[5.43], F282[5.47], L286[5.51], A290[5.55], Y293[5.58], T294[5.59], F326[6.38], A333[6.45], L337[6.49] | |
Endothelin ETB receptor, inactive, agonist bound, Human 5x93 | ||
5x93_EC | -12.9 | K175[3.26], F179[3.30], V223[4.47], V227[4.51], V230[4.54], V234[4.58], A237[4.61], I238[4.62] |
-12.5 | F112[1.43], I116[1.47], V152[2.55], P156[2.59], I157[2.60], Y160[2.63], F169, M173[3.24] | |
5x93_IC | -14.4 | I116[1.47], I117[1.48], S120[1.51], T121[1.52], Y124[1.55], V152[2.55], A400[8.57], L401[8.58], W404 |
-14.4 | L190[3.41], C193[3.44], A194[3.45], I197[3.48], D198[3.49], R201[3.52], E221[4.45], W276[5.41], F280[5.45], L284[5.49], I288[5.53] | |
-13.7 | L123[1.54], Y124[1.55], Y127[1.58], L145[2.48], L148[2.51], L149[2.52], V152[2.55], I153[2.56] | |
-12.8 | F278[5.43], F282[5.47], L286[5.51], A290[5.55], Y293[5.58], T294[5.59], F326[6.38], L337[6.49] | |
-12.8 | I138[2.41], L145[2.48], L149[2.52], V214[4.38], T218[4.42], A219[4.43], I222[4.46], V223[4.47], W226[4.50] | |
-12.9 | C327[6.39], V331[6.43], L334[6.46], P338[6.50], M374[7.41], I384[7.51], A385[7.52], L388[7.55], V389[7.56] | |
Free Fatty Acid receptor FFAR1 | ||
Free fatty acid receptor FFAR1, residues renumbered, inactive, Human 4phu | ||
4phu_EC | -13.3 | L231[4.55], L234[4.58], L235[4.59], P239[4.63], A242, S243, A246, S247, L253, W257 |
-13.2 | Q6, L7, F9, G10, V13, A14, A17, L18 | |
-12.8 | W131, A132, L135[2.38], C136[2.39], G139[2.42], F142[2.45], G143[2.46], G149[2.52], W150[2.53], L158[2.61] | |
-12.7 | L133, H137[2.40], V141[2.44], S178[3.29], P181[3.32], A182[3.33], S185[3.36], L189[3.40] | |
-12.5 | F192[3.43], L195[3.46], A199[3.50], L230[4.54], L234[4.58], A242, S243, A246, L253, W257 | |
4phu_IC | -12.4 | F20, V24, I27, R28, L53, L54, V57, V81, A85 |
-12.3 | A102[1.33], Y105[1.36], L106[1.37], L193[3.44], A196[3.47], I197[3.48], F200[3.51], C201[3.52] | |
-13.9 | Y44, A99[1.30], A102[1.33], A103[1.34], V126[1.57], I130, L189[3.40], L193[3.44], I197[3.48] | |
Histamine H1 receptor | ||
Histamine H1 receptor, inactive, Human 3rze | ||
3rze_EC | -14.1 | L154[4.52], L157[4.55], I160[4.58], P161[4.59], G164[4.62], W165, N166, H167, F190[5.38] |
-12.8 | S35[1.40], C38[1.43], V42[1.47], L46[1.51], L74[2.51], A78[2.55], P82[2.59], I85[2.62], L86[2.63], L89[2.66] | |
3rze_IC | -13.9 | L207[5.55], Y210[5.58], G418[6.38], A422[6.42], I425[6.45], L426[6.46], I429[6.49], I433[6.53] |
-13.8 | L39[1.44], V42[1.47], G43[1.48], L46[1.51], I482[8.57], L483[8.58], H484[8.59], I485 | |
-13.1 | L49[1.54], Y50[1.55], R53[1.58], V71[2.48], L74[2.51], I75[2.52], V79[2.56], F102[3.27], M106[3.31] | |
-13.3 | L64[2.41], V67[2.44], S68[2.45], V71[2.48], F102[3.27], I148[4.46], W152[4.50], F156[4.54] | |
Leukotriene BLT1 receptor | ||
Leukotriene BLT1 receptor, inactive, Human 5x33 | ||
5x33_EC | -14.5 | S28[1.42], M31[1.45], V32[1.46], L35[1.49], P36[1.50], P74[2.60], L77[2.63], H78[2.64], T81, W82 |
-13.8 | R93[3.28], Y97[3.32], V141[4.49], G145[4.53], F148[4.56], L149[4.57], T152[4.60], L155[4.63] | |
-13.4 | I19[1.33], A234[6.48], F235[6.49], P238[6.52], Q261[7.29], A265[7.33], V268[7.36], C269[7.37], L272[7.40] | |
-13.3 | A234[6.48], L237[6.51], P238[6.52], V241[6.55], V242[6.56], V245[6.59], L262[7.30], A265[7.33] | |
-13.0 | L71[2.57], T72[2.58], F75[2.61], F87[3.22], A90[3.25], G91[3.26], L94[3.29], C95[3.30] | |
-12.9 | L64[2.50], A90[3.25], R93[3.28], L94[3.29], Y97[3.32], I98[3.33], F148[4.56], L155[4.63] | |
5x33_IC | -15.1 | N61[2.47], L64[2.50], I98[3.33], V101[3.36], R137[4.45], L140[4.48], V141[4.49], W144[4.52], F148[4.56] |
-12.6 | L108[3.43], T111[3.46], A112[3.47], L115[3.50], D116[3.51], L139[4.47], A146[4.54], L150[4.58], F186[5.43] | |
-12.4 | F196[5.53], V200[5.57], Y203[5.60], A204[5.61], S207[5.64], I229[6.43], L230[6.44], L237[6.51] | |
Lysophosphatidic acid receptor 1 | ||
Lysophosphatidic acid receptor 1, inactive, Human 4z34 | ||
4z34_EC | -16.0, | F97[2.52], L122[3.26], L123[3.27], G126[3.30], L127[3.31], T130[3.34], I176[4.54], G179[4.57], S183[4.61] |
-14.8, | I268[6.45], T272[6.49], P273[6.50], V276[6.53], L280[6.57], D288[7.30], Y292[7.34], F296[7.38] | |
-12.8, | L215[5.48], F218[5.51], V219[5.52], V222[5.55], T272[6.49], V276[6.53], L279[6.56], L280[6.57], C283[6.60] | |
-12.0, | W45, M53[1.36], G54[1.37], I57[1.40], T58[1.41], I61[1.44], L65[1.48], F107[2.62] | |
-11.6, | M64[1.47], L65[1.48], L68[1.51], F96[2.51], L100[2.55], F103[2.58], Y104[2.59], F107[2.62] | |
4z34_IC | -13.0, | M71[1.54], Y75[1.58], Y86[2.41], A93[2.48], F97[2.52], I168[4.46], W172[4.50], I176[4.54] |
-13.2, | M64[1.47], L65[1.48], L68[1.51], L69[1.52], F96[2.51], L100[2.55], I325[8.57], L326[8.58] | |
Lysophosphatidic acid receptor 1, inactive, Human 4z35 | ||
4z35_EC | -14.7, | F97[2.52], L123[3.27], L127[3.31], T130[3.34], W172[4.50], I176[4.54], G179[4.57], A180[4.58], S183[4.61] |
-13.0, | I212[5.45], L215[5.48], V219[5.52], V276[6.53], L279[6.56], L280[6.57], C283[6.60], C284[6.61] | |
-12.4, | I268[6.45], I269[6.46], T272[6.49], P273[6.50], V276[6.53], L280[6.57], C284[6.61], C287, D288[7.30] | |
-11.7, | L140[3.44], M174[4.52], V177[4.55], M178[4.56], I181[4.59], W186, F209[5.42], F213[5.46] | |
4z35_IC | -14.9, | M71[1.54], I74[1.57], Y75[1.58], Y86[2.41], A89[2.44], A93[2.48], I168[4.46], W172[4.50], I176[4.54] |
Lysophosphatidic acid receptor 1, inactive, Human 4z36 | ||
4z36_EC | -14.8, | F97[2.52], L122[3.26], L123[3.27], G126[3.30], L127[3.31], T130[3.34], W172[4.50], I176[4.54], G179[4.57], A180[4.58], S183[4.61] |
-12.5, | I268[6.45], I269[6.46], T272[6.49], P273[6.50], V276[6.53], L280[6.57], D288[7.30], Y292[7.34] | |
-12.2, | I212[5.45], L215[5.48], F218[5.51], V219[5.52], V222[5.55], I268[6.45], T272[6.49], V276[6.53], L279[6.56], C283[6.60] | |
4z36_IC | -14.1, | M71[1.54], I74[1.57], Y75[1.58], Y86[2.41], A89[2.44], N90[2.45], I168[4.46], W172[4.50], I176[4.54] |
-12.6, | L140[3.44], I144[3.48], H147[3.51], I148[3.52], M174[4.52], M178[4.56], F213[5.46], L224[5.57] | |
-12.5, | L140[3.44], A141[3.45], I144[3.48], E145[3.49], I148[3.52], V167[4.45], V170[4.48], M178[4.56] | |
-13.0, | L68[1.51], M71[1.54], V72[1.55], Y75[1.58], V76[1.59], F96[2.51], F97[2.52], L100[2.55] | |
-12.4, | V222[5.55], F229[5.62], V261[6.38], G265[6.42], I268[6.45], I269[6.46], T272[6.49], V276[6.53] | |
-12.3, | I262[6.39], A266[6.43], I269[6.46], F296[7.38], L299[7.41], M306[7.48], Y313[7.55], R314[7.56] | |
Muscarinic AChR | ||
Muscarinic M1 receptor, inactive, Human 5cxv | ||
5cxv_EC | -14.2 | K20, Q24[1.31], F27[1.34], I28[1.35], T31[1.38], L86[2.65], T398[7.33], E401[7.36], L402[7.37], W405[7.40] |
-13.3 | L376[6.46], T379[6.49], P380[6.50], I383[6.53], M384[6.54], V387[6.57], C394, V395, P396[7.31], L399[7.34] | |
-12.6 | V25[1.32], G29[1.36], G33[1.40], S36[1.43], L37[1.44], V40[1.47], T76[2.55], N80[2.59], T84[2.63], L87[2.66], M88[2.67] | |
-12.6 | Q110[3.37], M114[3.41], L156[4.56], W164[4.64], F182, I188[5.38], T192[5.42], A195[5.45], A196[5.46] | |
5cxv_IC | -14.9 | Y62[2.41], L65[2.44], S66[2.45], C69[2.48], A143[4.43], I146[4.46], G147[4.47], W150[4.50], F154[4.54] |
-12.8 | I73[2.52], L104[3.31], V107[3.34], A143[4.43], L144[4.44], G147[4.47], L148[4.48], W150[4.50], L151[4.51], F154[4.54] | |
-12.7 | A369[6.39], L376[6.46], L406[7.41], V409[7.44], I413[7.48], M416[7.51], C417[7.52], L420[7.55] | |
-12.7 | S36[1.43], L37[1.44], V40[1.47], T41[1.48], L44[1.51], L45[1.52], I48[1.55], L432[8.57], L433[8.58], C435 | |
-12.1 | L34[1.41], L37[1.44], A38[1.45], T41[1.48], G42[1.49], L45[1.52], M416[7.51], L420[7.55], F429[8.54], L433[8.58] | |
Muscarinic M2 receptor, inactive, Human 3uon | ||
3uon_EC | -14.9 | I26[1.35], V29[1.38], A30[1.39], L33[1.42], T81[2.62], T84[2.65], V85[2.66], T423[7.36], W427[7.40], I431[7.44] |
-13.4 | N108[3.37], V111[3.40], M112[3.41], L154[4.56], W162[4.64], F180, F181, V186[5.38], T190[5.42], A193[5.45], A194[5.46] | |
-12.7 | V27[1.36], G31[1.40], S34[1.43], I38[1.47], N78[2.59], T81[2.62], L82[2.63], V85[2.66] | |
-12.3 | I398[6.46], A401[6.49], P402[6.50], V405[6.53], M406[6.54], C416, I417, P418[7.31], V421[7.34] | |
3uon_IC | -15.0 | L98[3.27], A101[3.30], L102[3.31], G141[4.43], I144[4.46], A145[4.47], W148[4.50], V149[4.51], F152[4.54] |
-13.9 | V29[1.38], L33[1.42], V36[1.45], I431[7.44], T434[7.47], I435[7.48], A438[7.51], A441[7.54], L442[7.55], K448[8.51] | |
-13.2 | L35[1.44], I38[1.47], I39[1.48], I42[1.51], L43[1.52], V46[1.55], L454[8.57], L455[8.58] | |
-12.8 | A391[6.39], L394[6.42], A395[6.43], I398[6.46], L428[7.41], I431[7.44], I435[7.48], C439[7.52], C443[7.56] | |
-12.5 | M112[3.41], L115[3.44], F119[3.48], F123[3.52], M143[4.45], L150[4.52], L154[4.56], T190[5.42], A193[5.45], A194[5.46] | |
-12.2 | F195[5.47], Y196[5.48], V199[5.51], T203[5.55], Y206[5.58], W207[5.59], S210[5.62], I397[6.45], A401[6.49], N404[6.52], V405[6.53] | |
-12.2 | S32[1.41], L35[1.44], V36[1.45], I39[1.48], L43[1.52], K448[8.51], F451[8.54], L455[8.58] | |
Muscarinic M2 receptor, active state, agonist bound, Human 4mqs | ||
4mqs_EC | -14.4 | E22[1.31], V23[1.32], F25[1.34], I26[1.35], V29[1.38], L33[1.42], I424[7.37], I431[7.44] |
-12.5 | L394[6.42], I398[6.46], P402[6.50], V405[6.53], M406[6.54], I409[6.57], I417, V421[7.34] | |
4mqs_IC | -14.6 | T203[5.55], Y206[5.58], W207[5.59], S210[5.62], I389[6.37], L390[6.38], L393[6.41], L394[6.42], I397[6.45] |
-13.6 | F63[2.44], S64[2.45], I71[2.52], L102[3.31], I144[4.46], A145[4.47], W148[4.50], F152[4.54], A156[4.58] | |
-13.4 | L35[1.44], I38[1.47], I39[1.48], I42[1.51], L43[1.52], V74[2.55], L454[8.57], L455[8.58] | |
-13.0 | A391[6.39], A395[6.43], I398[6.46], L428[7.41], I431[7.44], I435[7.48], A438[7.51], C439[7.52], C443[7.56] | |
-12.4 | V29[1.38], L33[1.42], V36[1.45], L43[1.52], I431[7.44], T434[7.47], I435[7.48], L442[7.55], F451[8.54] | |
-13.4 | L28[1.37], S32[1.41], L35[1.44], V36[1.45], I39[1.48], L43[1.52], F451[8.54], L455[8.58] | |
Muscarinic M3 receptor, inactive, Rat 4daj | ||
4daj_EC | -13.5 | N152[3.37], V155[3.40], M156[3.41], L198[4.56], A202[4.60], W206[4.64], F224, T234[5.42], A237[5.45], A238[5.46], M241[5.49], P242[5.50] |
-13.3 | V197[4.55], L198[4.56], P201[4.59], A202[4.60], F205[4.63], W206[4.64], Y208[4.66], F209[4.67] | |
-13.3 | I70[1.35], A71[1.36], L73[1.38], T74[1.39], L77[1.42], I128[2.65], L527[7.37], W530[7.40], L531[7.41], I534[7.44] | |
4daj_IC | -14.0 | Y104[2.41], L107[2.44], S108[2.45], C111[2.48], I115[2.52], I146[3.31], G189[4.47], W192[4.50], F196[4.54] |
-13.1 | M156[3.41], L159[3.44], V160[3.45], F163[3.48], F167[3.52], M187[4.45], I194[4.52], L198[4.56], A237[5.45], A238[5.46], M241[5.49] | |
-12.5 | A494[6.39], L497[6.42], A498[6.43], I501[6.46], T502[6.47], L531[7.41], I534[7.44], V538[7.48], C542[7.52], L545[7.55], C546[7.56] | |
Muscarinic M4 receptor, inactive, Human 5dsg | ||
5dsg_EC | -14.6 | E31[1.31], F34[1.34], I35[1.35], V38[1.38], I93[2.65], T433[7.33], I437[7.37], W440[7.40], L441[7.41], V444[7.44] |
-13.9 | H24, T29[1.29], M32[1.32], V33[1.33], A36[1.36], G40[1.40], L44[1.44], N87[2.59], I94[2.66] | |
-13.4 | L411[6.46], T414[6.49], P415[6.50], V418[6.53], M419[6.54], V422[6.57], C429, I430, P431[7.31], V434[7.34] | |
-13.0 | V103[3.23], D106[3.26], L107[3.27], F161[4.54], L169[4.62], F170[4.63], Q172[4.65], R178 | |
-12.2 | N117[3.37], M121[3.41], L163[4.56], F189, V195[5.38], T199[5.42], A202[5.45], A203[5.46] | |
5dsg_IC | -14.2 | Y69[2.41], F72[2.44], S73[2.45], I80[2.52], L111[3.31], G150[4.43], I153[4.46], A154[4.47], W157[4.50], F161[4.54] |
-14.0 | R400[6.35], F403[6.38], A404[6.39], L407[6.42], L411[6.46], L441[7.41], I448[7.48], C452[7.52], C456[7.56] | |
-13.4 | N117[3.37], M121[3.41], L124[3.44], I125[3.45], F128[3.48], F132[3.52], Y140, M152[4.45], L163[4.56], A202[5.45], A203[5.46] | |
-13.2 | L42[1.42], V45[1.45], G49[1.49], L52[1.52], V444[7.44], T447[7.47], I448[7.48], P450[7.50], A451[7.51], A454[7.54], F464[8.54], L468[8.58] | |
-12.1 | M54[1.54], K58[1.58], F72[2.44], C76[2.48], L79[2.51], I80[2.52], F84[2.56], L111[3.31] | |
-12.0 | I51[1.51], M54[1.54], L55[1.55], K58[1.58], F72[2.44], L79[2.51], A83[2.55], F84[2.56] | |
Neuropeptide Y1 receptor | ||
Neuropeptide Y1 receptor, inactive, Human 5zbh | ||
5zbh_EC | -12.9, | W129[3.41], L165[4.52], A168[4.55], S169[4.56], P172[4.59], Y211[5.38], L214[5.41], Q219[5.46] |
-12.5, | F84[2.48], I91[2.55], M92[2.56], F96[2.60], F108, G109[3.21], A111[3.23], M112[3.24] | |
-12.2, | V274[6.46], L277[6.49], P278[6.50], I281[6.53], F282[6.54], V285[6.57], L301[7.34], C305[7.38] | |
5zbh_IC | -14.5, | W129[3.41], V132[3.44], L133[3.45], V136[3.48], W148, H154[4.41], G158[4.45], V161[4.48], L165[4.52] |
-13.2, | L66[1.58], I77[2.41], V80[2.44], N81[2.45], F84[2.48], Y156[4.43], I159[4.46], W163[4.50] | |
Neuropeptide Y1 receptor, inactive, Human 5zbq | ||
5zbq_EC | -13.5, | L165[4.52], A168[4.55], S169[4.56], P172[4.59], I175[4.62], Y176[4.63], L214[5.41], L218[5.45] |
-12.2, | M39[1.31], T42[1.34], L43[1.35], A46[1.38], L300[7.33], L304[7.37], L307[7.40], I311[7.44] | |
-12.0, | I51[1.43], V55[1.47], L59[1.51], I91[2.55], P95[2.59], F96[2.60], V99[2.63], F108 | |
-12.8, | I40[1.32], A44[1.36], G48[1.40], I51[1.43], I52[1.44], F98[2.62], V99[2.63], L102[2.66] | |
5zbq_IC | -13.4, | L66[1.58], I77[2.41], V80[2.44], F84[2.48], Y156[4.43], I159[4.46], W163[4.50], V167[4.54] |
-12.6, | S267[6.39], V274[6.46], T308[7.41], V315[7.48], I318[7.51], F319[7.52], F322[7.55], Q328[8.51] | |
Neurotensin NTS1 receptor | ||
Neurotensin receptor NTS1, active intermediate, agonist bound, Rat 3zev | ||
3zev_EC | -13.6 | D60.B, Y62.B[1.30], S63.B[1.31], L66.B[1.34], V67.B[1.35], I70.B[1.38], Y349.B[7.33], M352.B[7.36], L353.B[7.37], L357.B[7.41], V360.B[7.44] |
-12.6 | L199.B[4.55], L200.B[4.56], I202.B[4.58], P203.B[4.59], F206.B[4.62], T207.B[4.63], V229.B, T233.B[5.34], V237.B[5.38] | |
-12.4 | L247.B[5.48], L251.B[5.52], L322.B[6.49], V326.B[6.53], L329.B[6.56], M330.B[6.57], Y333.B[6.60], I334.B[6.61] | |
-12.7 | V319.B[6.46], L322.B[6.49], P323.B[6.50], V326.B[6.53], M330.B[6.57], I334.B[6.61], L343.B[7.27], F346.B[7.30], F350.B[7.34] | |
-12.1 | A140.B[3.23], R143.B[3.26], G144.B[3.27], F147.B[3.30], W194.B[4.50], L195.B[4.51], A198.B[4.54], L205.B[4.61] | |
-12.6 | L115.B[2.52], L119.B[2.56], V123.B[2.60], A136.B, F137.B, G138.B[3.21], G141.B[3.24], L148.B[3.31] | |
3zev_IC | -14.9 | F75.B[1.43], T79.B[1.47], V80.B[1.48], S83.B[1.51], V84.B[1.52], F87.B[1.55], L118.B[2.55], T383.B[8.57], L384.B[8.58], C386.B |
-14.2 | L247.B[5.48], L251.B[5.52], S254.B[5.55], T258.B[5.59], R311.B[6.38], V314.B[6.41], I315.B[6.42], V318.B[6.45], L322.B[6.49] | |
-12.9 | Y104.B[2.41], L111.B[2.48], F147.B[3.30], I190.B[4.46], S191.B[4.47], W194.B[4.50], L195.B[4.51], A198.B[4.54] | |
-13.3 | A69.B[1.37], I70.B[1.38], A73.B[1.41], V77.B[1.45], I367.B[7.51], N370.B[7.54], F380.B[8.54], L381.B[8.55] | |
-12.5 | A312.B[6.39], I315.B[6.42], A316.B[6.43], V319.B[6.46], C320.B[6.47], L353.B[7.37], L357.B[7.41], V360.B[7.44], L368.B[7.52] | |
-12.8 | I70.B[1.38], L74.B[1.42], A356.B[7.40], L357.B[7.41], V360.B[7.44], I364.B[7.48], I367.B[7.51], L371.B[7.55] | |
Neurotensin receptor NTS1, active intermediate, agonist bound, Rat 4buo | ||
4buo_EC | -14.3 | D60, Y62[1.30], S63[1.31], L66[1.34], V67[1.35], I70[1.38], Y349[7.33], M352[7.36], L353[7.37], A356[7.40], L357[7.41], V360[7.44] |
4buo_IC | -13.6 | F75[1.43], T79[1.47], V80[1.48], S83[1.51], V84[1.52], F87[1.55], L118[2.55], P122[2.59], T383[8.57], L384[8.58] |
Neurotensin receptor NTS1, active intermediate, agonist bound, Rat 4bv0 | ||
4bv0_EC | -14.5 | D60, S63[1.31], L66[1.34], V67[1.35], I70[1.38], Y349[7.33], L353[7.37], A356[7.40], L357[7.41], V360[7.44] |
-12.7 | L111[2.48], L115[2.52], F119[2.56], F137, G138[3.21], A140[3.23], G141[3.24], L148[3.31] | |
4bv0_IC | -14.6 | T79[1.47], V80[1.48], G83[1.51], V84[1.52], F87[1.55], L118[2.55], F119[2.56], T383[8.57], L384[8.58], C386, L387 |
-14.0 | S254[5.55], N257[5.58], T258[5.59], A261[5.62], R311[6.38], V314[6.41], I315[6.42], V318[6.45], L322[6.49] | |
-13.5 | Y104[2.41], G107[2.44], S108[2.45], L111[2.48], F147[3.30], I190[4.46], S191[4.47], W194[4.50], A198[4.54] | |
-13.5 | G83[1.51], L86[1.54], F87[1.55], A90[1.58], L111[2.48], L114[2.51], L115[2.52], F119[2.56] | |
Neurotensin receptor NTS1, active state, Rat 4grv | ||
4grv_EC | -14.0 | D60, S63[1.31], L66[1.34], V67[1.35], I70[1.38], Y349[7.33], M352[7.36], L353[7.37], A356[7.40], L357[7.41], A360[7.44] |
-12.8 | K235[5.36], V236[5.37], Q239[5.40], V240[5.41], F243[5.44], M244[5.45], F248[5.49], Y333[6.60] | |
-12.8 | L199[4.55], L200[4.56], I202[4.58], P203[4.59], F206[4.62], T207[4.63], V229, V237[5.38] | |
-13.0 | F75[1.43], T79[1.47], L118[2.55], P122[2.59], L125[2.62], Y126[2.63], W130[2.67], V131[2.68] | |
4grv_IC | -13.5 | Y104[2.41], S108[2.45], L111[2.48], F147[3.30], L148[3.31], K187[4.43], I190[4.46], S191[4.47], W194[4.50] |
-13.3 | M250[5.51], S254[5.55], T258[5.59], R311[6.38], V314[6.41], I315[6.42], V318[6.45], L322[6.49] | |
-12.6 | I70[1.38], L74[1.42], L308[6.35], A312[6.39], I315[6.42], A316[6.43], V319[6.46], C320[6.47], A356[7.40], L357[7.41], A360[7.44], I364[7.48] | |
-12.2 | F75[1.43], T79[1.47], V80[1.48], S83[1.51], V84[1.52], F87[1.55], L118[2.55], P122[2.59] | |
Neurotensin receptor NTS1, active state, Rat 4xee | ||
4xee_EC | -14.5 | D60, S63[1.31], L66[1.34], I70[1.38], Y349[7.33], M352[7.36], L353[7.37], A356[7.40], L357[7.41], A360[7.44] |
-13.3 | L247[5.48], L251[5.52], L322[6.49], V326[6.53], L329[6.56], M330[6.57], Y333[6.60], I334[6.61] | |
-12.9 | A196[4.52], L199[4.55], L200[4.56], I202[4.58], P203[4.59], F206[4.62], T207[4.63], T233[5.34], V237[5.38] | |
-12.7 | L72[1.40], F75[1.43], V76[1.44], T79[1.47], L125[2.62], Y126[2.63], W130[2.67], V131[2.68] | |
-12.5 | A140[3.23], R143[3.26], G144[3.27], F147[3.30], L195[4.51], A198[4.54], I202[4.58], L205[4.61] | |
-12.6 | I61[1.29], V65[1.33], T68[1.36], A69[1.37], L72[1.40], A73[1.41], V76[1.44], W130[2.67] | |
-12.5 | F75[1.43], T79[1.47], L118[2.55], P122[2.59], V123[2.60], Y126[2.63], A136, F137 | |
4xee_IC | -14.2 | S83[1.51], V84[1.52], L86[1.54], F87[1.55], L111[2.48], L114[2.51], L115[2.52], L118[2.55], L119[2.56] |
-13.3 | Y104[2.41], S108[2.45], L111[2.48], F147[3.30], L148[3.31], K187[4.43], I190[4.46], S191[4.47], W194[4.50] | |
-13.3 | F75[1.43], T79[1.47], V80[1.48], S83[1.51], V84[1.52], L118[2.55], T383[8.57], L384[8.58] | |
-13.2 | M250[5.51], S254[5.55], T258[5.59], R311[6.38], V314[6.41], I315[6.42], V318[6.45], L322[6.49] | |
-13.0 | I70[1.38], L74[1.42], A312[6.39], A316[6.43], A356[7.40], L357[7.41], A360[7.44], I364[7.48], L368[7.52] | |
-12.8 | L158[3.41], K188[4.44], F189[4.45], A192[4.48], I193[4.49], A196[4.52], L200[4.56], V240[5.41], M244[5.45] | |
Neurotensin receptor NTS1, active state, Rat 4xes | ||
4xes_EC | -13.3 | D60, S63[1.31], L66[1.34], V67[1.35], I70[1.38], L74[1.42], Y349[7.33], M352[7.36], L353[7.37], A356[7.40], A360[7.44] |
-12.9 | F246[5.47], L247[5.48], M250[5.51], L251[5.52], L322[6.49], V326[6.53], L329[6.56], M330[6.57], I334[6.61] | |
-12.7 | L118[2.55], L119[2.56], V123[2.60], F137, G138[3.21], A140[3.23], G141[3.24], C142[3.25] | |
4xes_IC | -14.2 | A69[1.37], A73[1.41], V76[1.44], V77[1.45], V80[1.48], F380[8.54], L381[8.55], T383[8.57] |
-13.6 | L111[2.48], L115[2.52], L119[2.56], L148[3.31], K187[4.43], I190[4.46], S191[4.47], W194[4.50] | |
-13.4 | F246[5.47], M250[5.51], S254[5.55], T258[5.59], R311[6.38], V314[6.41], V318[6.45], L322[6.49] | |
-13.1 | I70[1.38], L74[1.42], V77[1.45], A356[7.40], L357[7.41], A360[7.44], I364[7.48], I367[7.51], F380[8.54] | |
-13.0 | S83[1.51], L86[1.54], F87[1.55], L111[2.48], L114[2.51], L115[2.52], L118[2.55], L119[2.56] | |
-12.7 | I70[1.38], L74[1.42], A312[6.39], A316[6.43], A356[7.40], L357[7.41], A360[7.44], I364[7.48], L368[7.52] | |
-13.0 | F75[1.43], T79[1.47], V80[1.48], S83[1.51], V84[1.52], F87[1.55], L118[2.55], P122[2.59] | |
Neurotensin receptor NTS1, active state, Rat 5t04 | ||
5t04_EC | -13.1 | D60, S63[1.31], L66[1.34], V67[1.35], I70[1.38], L74[1.42], Y349[7.33], M352[7.36], L353[7.37], L357[7.41], A360[7.44] |
-12.7 | D139[3.22], A140[3.23], R143[3.26], G144[3.27], F147[3.30], L148[3.31], L195[4.51], A198[4.54], L205[4.61] | |
-13.3 | L111[2.48], L115[2.52], L119[2.56], F137, A140[3.23], G141[3.24], G144[3.27], L148[3.31] | |
-12.9 | L247[5.48], M250[5.51], L251[5.52], L322[6.49], V326[6.53], L329[6.56], M330[6.57], Y333[6.60], I334[6.61] | |
-12.5 | T68[1.36], L72[1.40], F75[1.43], T79[1.47], P122[2.59], L125[2.62], Y126[2.63], W130[2.67], V131[2.68] | |
-12.2 | V319[6.46], L322[6.49], P323[6.50], V326[6.53], M330[6.57], I334[6.61], F346[7.30], F350[7.34] | |
5t04_IC | -14.0 | M250[5.51], S254[5.55], T258[5.59], R311[6.38], V314[6.41], I315[6.42], V318[6.45], L322[6.49] |
-13.5 | Y104[2.41], L111[2.48], L115[2.52], L119[2.56], L148[3.31], K187[4.43], I190[4.46], S191[4.47], W194[4.50] | |
-13.0 | L86[1.54], F87[1.55], A90[1.58], L111[2.48], L114[2.51], L115[2.52], L118[2.55], L119[2.56] | |
-12.3 | I70[1.38], L308[6.35], A312[6.39], I315[6.42], A316[6.43], V319[6.46], C320[6.47], L353[7.37], A356[7.40], L357[7.41], A360[7.44], I364[7.48], L368[7.52] | |
Opioid receptor | ||
Opioid delta receptor, inactive, Mouse 4ej4 | ||
4ej4_EC | -12.7 | V271[6.45], V272[6.46], A275[6.49], P276[6.50], I279[6.53], F280[6.54], V283[6.57], I289, V296[7.31] |
-12.7 | L175[4.52], G178[4.55], V179[4.56], P182[4.59], M186[4.63], F202, W209[5.34], V212[5.37], T213[5.38], F220[5.45] | |
-12.6 | T53[1.36], S57[1.40], A61[1.44], L65[1.48], P103[2.58], S106[2.61], A107[2.62], L110[2.65], M111[2.66], F116 | |
-12.6 | F218[5.43], F222[5.47], V223[5.48], I226[5.51], L227[5.52], I279[6.53], I282[6.56], V283[6.57], L286[6.60], V287[6.61] | |
4ej4_IC | -14.6 | F89[2.44], N90[2.45], L93[2.48], L97[2.52], Y130[3.34], K166[4.43], N169[4.46], I170[4.47], W173[4.50] |
-12.6 | V144[3.48], Y147[3.51], I148[3.52], V224[5.49], L227[5.52], I228[5.53], V231[5.56], C232[5.57] | |
-12.3 | R261[6.35], V265[6.39], A269[6.43], V272[6.46], L302[7.37], L306[7.41], L313[7.48], L317[7.52] | |
-12.8 | F137[3.41], M141[3.45], V144[3.48], F159, K164[4.41], L167[4.44], I168[4.45], L175[4.52], F220[5.45], V224[5.49], P225[5.50] | |
-13.7 | F222[5.47], R261[6.35], L264[6.38], V265[6.39], G268[6.42], V271[6.45], V272[6.46], A275[6.49], I279[6.53] | |
Opioid delta receptor, inactive, Human 4n6h | ||
4n6h_EC | -15.1 | F133[3.37], F137[3.41], L175[4.52], G178[4.55], V179[4.56], F202, W209[5.34], V212[5.37], T213[5.38], C216[5.41], F220[5.45] |
-13.7 | V272[6.46], A275[6.49], P276[6.50], I279[6.53], F280[6.54], V283[6.57], I289, V296[7.31], A299[7.34], C303[7.38] | |
-12.7 | S44[1.27], A47[1.30], L48[1.31], A51[1.34], L55[1.38], P294[7.29], A298[7.33], L302[7.37] | |
-12.4 | F218[5.43], F222[5.47], I226[5.51], A275[6.49], I279[6.53], I282[6.56], V283[6.57], V287[6.61] | |
-12.0 | T53[1.36], S57[1.40], A61[1.44], L65[1.48], P103[2.58], S106[2.61], A107[2.62], L110[2.65] | |
-11.9 | L64[1.47], M71[1.54], L93[2.48], A96[2.51], L97[2.52], S100[2.55], L119[3.23], L120[3.24], A123[3.27] | |
-12.3 | L93[2.48], L119[3.23], K122[3.26], A123[3.27], S126[3.30], Y130[3.34], W173[4.50], M184[4.61] | |
4n6h_IC | -13.6 | I74[1.57], V75[1.58], K81, I86[2.41], F89[2.44], K166[4.43], N169[4.46], I170[4.47], W173[4.50] |
-13.6 | L64[1.47], L65[1.48], V68[1.51], L69[1.52], F72[1.55], L332[8.57], C333[8.58], K335[8.60], P336 | |
Opioid delta receptor, inactive, Human 4rwa | ||
4rwa_EC | -13.4 | S44[1.27], A47[1.30], L48[1.31], A51[1.34], L55[1.38], P294[7.29], L295[7.30], A298[7.33], L302[7.37] |
-13.2 | V272[6.46], A275[6.49], P276[6.50], I279[6.53], F280[6.54], V283[6.57], I289, V296[7.31], A299[7.34] | |
-12.7 | F137[3.41], L175[4.52], V179[4.56], Y208[5.33], W209[5.34], V212[5.37], T213[5.38], C216[5.41], F220[5.45] | |
-12.6 | V174[4.51], L175[4.52], G178[4.55], V181[4.58], P182[4.59], V185[4.62], M186[4.63], W209[5.34] | |
4rwa_IC | -14.3 | A58[1.41], A61[1.44], V62[1.45], L65[1.48], L69[1.52], F329[8.54], R330[8.55], L332[8.57], C333[8.58] |
-13.1 | V75[1.58], K81, I86[2.41], F89[2.44], L93[2.48], Y130[3.34], K166[4.43], I170[4.47], W173[4.50] | |
-12.4 | F222[5.47], I226[5.51], T230[5.55], Y233[5.58], L237[5.62], L264[6.38], V271[6.45], A275[6.49], I279[6.53] | |
-12.9 | L55[1.38], A58[1.41], V62[1.45], V316[7.51], A319[7.54], F320[7.55], F329[8.54], R330[8.55] | |
-12.4 | V68[1.51], M71[1.54], F72[1.55], V75[1.58], R76[1.59], L93[2.48], L97[2.52], S100[2.55] | |
-12.3 | F137[3.41], T140[3.44], M141[3.45], V144[3.48], Y147[3.51], I148[3.52], H152[3.56], L175[4.52], F220[5.45], V224[5.49], I228[5.53] | |
-12.4 | L55[1.38], L306[7.41], A309[7.44], L313[7.48], V316[7.51], L317[7.52], F320[7.55], L321[7.56] | |
Opioid delta receptor, inactive, Human 4rwd | ||
4rwd_EC | -14.5 | L175[4.52], G178[4.55], V179[4.56], P182[4.59], M186[4.63], F202, W209[5.34], D210[5.35], V212[5.37], T213[5.38], C216[5.41], F220[5.45] |
-13.4 | V272[6.46], A275[6.49], P276[6.50], I279[6.53], F280[6.54], V283[6.57], I289, V296[7.31], A299[7.34], C303[7.38] | |
-12.6 | F218[5.43], F222[5.47], V223[5.48], I226[5.51], I279[6.53], I282[6.56], V283[6.57], V287[6.61] | |
-12.0 | S57[1.40], C60[1.43], A61[1.44], P103[2.58], S106[2.61], A107[2.62], L110[2.65], M111[2.66] | |
4rwd_IC | -16.1 | I74[1.57], V75[1.58], K81, I86[2.41], F89[2.44], N90[2.45], L93[2.48], Y130[3.34], K166[4.43], N169[4.46], I170[4.47], W173[4.50], S177[4.54] |
-12.8 | F137[3.41], T140[3.44], V144[3.48], Y147[3.51], K155, F159, L175[4.52], F220[5.45], V224[5.49], P225[5.50], I228[5.53] | |
-12.5 | F222[5.47], V223[5.48], I226[5.51], T230[5.55], Y233[5.58], L237[5.62], L264[6.38], V271[6.45] | |
Opioid kappa receptor, inactive, Human 4djh | ||
4djh_EC | -14.0 | Y66[1.39], S67[1.40], F70[1.43], V71[1.44], P113[2.58], S116[2.61], T117[2.62], L120[2.65] |
-13.5 | F143[3.37], F147[3.41], L185[4.52], S188[4.55], V189[4.56], S192[4.59], L196[4.63], W222[5.34], F225[5.37], M226[5.38], C229[5.41], F233[5.45] | |
4djh_IC | -13.6 | F99[2.44], L103[2.48], L107[2.52], I137[3.31], Y140[3.34], K176[4.43], I180[4.47], W183[4.50] |
-12.4 | A64[1.37], S67[1.40], V68[1.41], V71[1.44], V72[1.45], V75[1.48], L79[1.52], F341[8.54], C345[8.58] | |
-11.9 | Y246[5.58], I250[5.62], L277[6.38], A281[6.42], V284[6.45], V285[6.46], T288[6.49], P289[6.50] | |
-11.8 | R274[6.35], V278[6.39], V282[6.43], V285[6.46], L318[7.41], T321[7.44], L325[7.48], L329[7.52], L333[7.56] | |
Opioid kappa receptor,active, with cholesterol, Human 6b73 | ||
6b73_EC | -12.9 | F147[3.41], L185[4.52], S188[4.55], V189[4.56], S192[4.59], L196[4.63], W222[5.34], F225[5.37], M226[5.38], F233[5.45], I237[5.49] |
-12.6 | V284[6.45], V285[6.46], T288[6.49], P289[6.50], I292[6.53], F293[6.54], V296[6.57], T302 | |
-12.0 | L107[2.52], K132[3.26], I133[3.27], S136[3.30], I137[3.31], Y140[3.34], N141[3.35], I194[4.61] | |
-12.0 | F231[5.43], F235[5.47], V239[5.51], L240[5.52], I292[6.53], L295[6.56], V296[6.57], L299[6.60] | |
-12.0 | F70[1.43], V71[1.44], V75[1.48], P113[2.58], S116[2.61], T117[2.62], L120[2.65], M121[2.66] | |
6b73_IC | -13.4 | M90, I96[2.41], F99[2.44], N100[2.45], L103[2.48], Y140[3.34], K176[4.43], N179[4.46], W183[4.50] |
-13.2 | V154[3.48], Y157[3.51], I158[3.52], V236[5.48], I237[5.49], L240[5.52], I241[5.53], V244[5.56], C245[5.57] | |
Opioid mu receptor, inactive, with cholesterol, Mouse 4dkl | ||
4dkl_EC | -14.2 | L194[4.52], A197[4.55], I198[4.56], F221, W228[5.34], L231[5.37], L232[5.38], C235[5.41] |
-14.0 | I290[6.45], V291[6.46], T294[6.49], P295[6.50], I298[6.53], Y299[6.54], I302[6.57], I308, P309, F313[7.30], S317[7.34] | |
-12.7 | F237[5.43], F241[5.47], I242[5.48], V245[5.51], I298[6.53], I301[6.56], I302[6.57], L305[6.60], I306[6.61] | |
4dkl_IC | -13.7 | F108[2.44], L112[2.48], L116[2.52], I146[3.31], Y149[3.34], K185[4.43], V189[4.47], W192[4.50] |
-13.2 | V245[5.51], Y252[5.58], L283[6.38], V284[6.39], V286[6.41], A287[6.42], I290[6.45], T294[6.49], I298[6.53] | |
-12.3 | Y106[2.42], C159[3.44], T160[3.45], V163[3.48], D164[3.49], V187[4.45], L194[4.52], F239[5.45], I247[5.53] | |
Opioid mu receptor, active, with cholesterol, Mouse 5c1m | ||
5c1m_EC | -15.4 | L194[4.52], A197[4.55], I198[4.56], P201[4.59], M205[4.63], F221, S222, W228[5.34], L231[5.37], C235[5.41], F239[5.45] |
-14.4 | I290[6.45], T294[6.49], P295[6.50], I298[6.53], Y299[6.54], I302[6.57], I308, F313[7.30], Q314[7.31], S317[7.34] | |
-13.6 | V291[6.46], P295[6.50], Y299[6.54], I302[6.57], I308, F313[7.30], Q314[7.31], S317[7.34], F320[7.37], C321[7.38], L324[7.41] | |
5c1m_IC | -13.6 | Y166[3.51], I238[5.44], F239[5.45], M243[5.49], L246[5.52], I247[5.53], V250[5.56], C251[5.57], L254[5.60] |
-13.1 | M99, I105[2.41], F108[2.44], N109[2.45], L112[2.48], I146[3.31], Y149[3.34], K185[4.43], N188[4.46], W192[4.50] | |
-12.6 | T249[5.55], Y252[5.58], G253[5.59], I256[5.62], V282[6.37], L283[6.38], V286[6.41], I290[6.45] | |
-12.6 | F237[5.43], F241[5.47], I242[5.48], V245[5.51], L246[5.52], T249[5.55], G253[5.59], I256[5.62], L283[6.38], V286[6.41], I290[6.45] | |
-12.5 | F87[1.51], M90[1.54], Y91[1.55], V94[1.58], R95[1.59], L112[2.48], L116[2.52], I146[3.31] | |
-12.5 | L74[1.38], I77[1.41], V81[1.45], F84[1.48], L88[1.52], T327[7.44], C330[7.47], L331[7.48], V334[7.51], F338[7.55] | |
Opioid NOP receptor, inactive, Human 4ea3 | ||
4ea3_EC | -13.5 | L95[2.48], L99[2.52], K124[3.26], T125[3.27], A128[3.30], Y132[3.34], W175[4.50], V183[4.58], A186[4.61], I187[4.62] |
-13.3 | F135[3.37], F139[3.41], L177[4.52], V180[4.55], V181[4.56], P184[4.59], F215[5.38], C218[5.41], I219[5.42], F222[5.45], V226[5.49] | |
-11.9 | L50[1.31], A299[7.33], I300[7.34], F303[7.37], C304[7.38], L307[7.41], V310[7.44], L314[7.48] | |
4ea3_IC | -14.7 | L77[1.58], F91[2.44], L95[2.48], Y132[3.34], Q168[4.43], N171[4.46], V172[4.47], W175[4.50], S179[4.54], V183[4.58] |
-13.0 | I231[5.54], S232[5.55], Y235[5.58], S236[5.59], I239[5.62], L266[6.38], A270[6.42], V273[6.45], G274[6.46], T277[6.49] | |
-12.7 | L57[1.38], A60[1.41], G64[1.45], G68[1.49], L71[1.52], C313[7.47], P316[7.50], I317[7.51], A320[7.54], F330[8.54] | |
-12.7 | F139[3.41], T142[3.44], A143[3.45], V146[3.48], V170[4.45], L177[4.52], F222[5.45], V230[5.53] | |
-13.3 | V146[3.48], Y149[3.51], F222[5.45], V226[5.49], L229[5.52], V230[5.53], V233[5.56], C234[5.57] | |
-12.8 | R263[6.35], L266[6.38], V267[6.39], A270[6.42], V271[6.43], G274[6.46], P278[6.50], L307[7.41] | |
-12.7 | L57[1.38], V267[6.39], V271[6.43], L307[7.41], V310[7.44], L314[7.48], L318[7.52], L322[7.56] | |
Opioid NOP receptor, inactive, Human5dhg | ||
5dhg_EC | -13.7 | L95.B[2.48], L99.B[2.52], K124.B[3.26], T125.B[3.27], A128.B[3.30], Y132.B[3.34], W175.B[4.50], V183.B[4.58], A186.B[4.61], I187.B[4.62] |
-12.9 | F139.B[3.41], L177.B[4.52], V180.B[4.55], V181.B[4.56], P184.B[4.59], M188.B[4.63], P205.B, W211.B[5.34], F215.B[5.38], I219.B[5.42], F222.B[5.45] | |
-11.8 | L50.B[1.31], T296.B[7.30], A299.B[7.33], I300.B[7.34], F303.B[7.37], L307.B[7.41], V310.B[7.44], L314.B[7.48] | |
5dhg_IC | -14.1 | L77.B[1.58], F91.B[2.44], L95.B[2.48], Y132.B[3.34], Q168.B[4.43], V172.B[4.47], W175.B[4.50], S179.B[4.54] |
Opioid NOP receptor, inactive, Human5dhh | ||
5dhh_EC | -12.9 | F135[3.37], F139[3.41], L177[4.52], V181[4.56], P184[4.59], M188[4.63], P205, W211[5.34], F215[5.38], F222[5.45] |
-12.5 | L99[2.52], A121[3.23], K124[3.26], T125[3.27], A128[3.30], I129[3.31], Y132[3.34], A186[4.61] | |
5dhh_IC | -14.5 | I88[2.41], F91[2.44], L95[2.48], Y132[3.34], Q168[4.43], N171[4.46], V172[4.47], W175[4.50], V183[4.58] |
-13.2 | F139[3.41], T142[3.44], A143[3.45], V146[3.48], V170[4.45], L177[4.52], F222[5.45], V230[5.53] | |
-13.2 | C70[1.51], Y74[1.55], L77[1.58], R78[1.59], T98[2.51], L99[2.52], L102[2.55], I129[3.31] | |
-12.8 | V146[3.48], Y149[3.51], F222[5.45], V226[5.49], L229[5.52], V230[5.53], V233[5.56], C234[5.57], L237[5.60] | |
Opsin | ||
Opsin, Bovine 3cap | ||
3cap_EC | -14.2 | V81[2.48], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.3 | W35[1.30], Q36[1.31], M39[1.34], Y43[1.38], L46[1.41], L50[1.45], I286[7.33], F293[7.40] | |
-12.9 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-12.7 | L216[5.51], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], T277[6.60], H278[6.61] | |
-12.5 | I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], Y96[2.63], F105 | |
-12.3 | A158[4.47], W161[4.50], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-12.0 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], I286[7.33], F287[7.34], I290[7.37], F294[7.41] | |
3cap_IC | -14.3 | F208[5.43], F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60], L266[6.49] |
-13.0 | W126[3.41], I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
-12.9 | I133[3.48], E134[3.49], V137[3.52], F148, M155[4.44], G156[4.45], F159[4.48], V162[4.51] | |
-12.5 | T62[1.57], Y74[2.41], L77[2.44], N78[2.45], V81[2.48], F85[2.52], F116[3.31], W161[4.50] | |
Opsin, Bovine 3dqb | ||
3dqb_EC | -14.2 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.1 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F283, F287[7.34] | |
-13.1 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-12.6 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], L46[1.41], I286[7.33], F293[7.40] | |
-13.7 | L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], H278[6.61] | |
-13.0 | I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], Y96[2.63], F105 | |
-13.0 | W175, S202[5.37], F203[5.38], I205[5.40], Y206[5.41], V209[5.44], V210[5.45], I214[5.49] | |
3dqb_IC | -14.0 | F208[5.43], F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60] |
-13.5 | L59[1.54], T62[1.57], V63[1.58], R69, L77[2.44], V81[2.48], F85[2.52], F116[3.31], W161[4.50] | |
-13.2 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
Opsin, Bovine 4j4q | ||
4j4q_EC | -15.2 | F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28] |
-13.5 | V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175, Y206[5.41] | |
-12.8 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F283, F287[7.34] | |
4j4q_IC | -13.2 | F208[5.43], F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], Q225[5.60] |
-12.7 | Y43[1.38], L46[1.41], R252[6.35], I256[6.39], F293[7.40], Y301[7.48], V304[7.51], M309[7.56] | |
-12.4 | F220[5.55], G224[5.59], V227[5.62], V254[6.37], I255[6.38], V258[6.41], I259[6.42], L262[6.45] | |
Opsin, Bovine 4pxf | ||
4pxf_EC | -14.5 | F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], C110[3.25], L112[3.27], E113[3.28] |
-13.4 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], F293[7.40] | |
-13.0 | L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], T277[6.60], H278[6.61] | |
-13.0 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F283, F287[7.34] | |
-12.2 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], P170[4.59], V173[4.62], W175, Y206[5.41] | |
-12.4 | W175, S202[5.37], F203[5.38], I205[5.40], Y206[5.41], V209[5.44], V210[5.45], I214[5.49] | |
4pxf_IC | -12.9 | F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60], L266[6.49] |
-12.8 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
Opsin, Bovine 4x1h | ||
4x1h_EC | -14.6 | F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28] |
-13.2 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F283, F287[7.34] | |
-12.8 | Q36[1.31], F37[1.32], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], F293[7.40] | |
-12.3 | W175, E201[5.36], S202[5.37], I205[5.40], Y206[5.41], V209[5.44], V210[5.45], I214[5.49] | |
-12.4 | F159[4.48], V162[4.51], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175, Y206[5.41] | |
4x1h_IC | -14.7 | L59[1.54], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] |
-13.2 | F208[5.43], F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], Q225[5.60] | |
-12.7 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], V210[5.45], I214[5.49], V218[5.53], F221[5.56] | |
Opsin, Bovine 5te3 | ||
5te3_EC | -14.5 | F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28] |
-14.1 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175 | |
-13.6 | Q36[1.31], F37[1.32], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], F293[7.40] | |
-12.8 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-13.5 | L216[5.51], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], T277[6.60], H278[6.61] | |
-12.4 | I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], Y96[2.63], F105 | |
5te3_IC | -12.9 | F208[5.43], F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], L266[6.49] |
-12.4 | W126[3.41], I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56] | |
-12.3 | Y74[2.41], L77[2.44], N78[2.45], V81[2.48], F85[2.52], F116[3.31], V157[4.46], W161[4.50] | |
-12.2 | F56[1.51], L59[1.54], Y60[1.55], V63[1.58], Q64[1.59], L84[2.51], F85[2.52], F88[2.55] | |
Opsin, Bovine 5wkt | ||
5wkt_EC | -14.2 | F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.2 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F283, F287[7.34] | |
-13.0 | Q36[1.31], F37[1.32], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], F293[7.40] | |
-12.5 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
5wkt_IC | -13.7 | F208[5.43], F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], Q225[5.60] |
-12.3 | W126[3.41], I133[3.48], Y136[3.51], V137[3.52], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
Opsin, Bovine 6fk6 | ||
6fk6_EC | -14.6 | F85[2.52], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-12.9 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], A42[1.37], Y43[1.38], L46[1.41], M183, I286[7.33], F293[7.40] | |
-12.8 | F208[5.43], L216[5.51], L262[6.45], W265[6.48], L266[6.49], A269[6.52], A272[6.55], F273[6.56], F276[6.59] | |
-12.6 | F159[4.48], M163[4.52], A166[4.55], P170[4.59], V173[4.62], W175, Y206[5.41], V210[5.45] | |
-12.2 | A158[4.47], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-12.1 | F85[2.52], F115[3.30], F116[3.31], L119[3.34], W161[4.50], L165[4.54], A169[4.58], L172[4.61], V173[4.62] | |
6fk6_IC | -13.7 | I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60], W265[6.48] |
-13.7 | L59[1.54], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] | |
-12.9 | I133[3.48], Y136[3.51], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56] | |
Opsin, Bovine 6fk7 | ||
6fk7_EC | -14.3 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.6 | I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], I286[7.33], F287[7.34], I290[7.37] | |
-13.6 | W35[1.30], Q36[1.31], M39[1.34], Y43[1.38], L46[1.41], L50[1.45], F293[7.40], F294[7.41], T297[7.44] | |
-12.9 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175 | |
-12.3 | F85[2.52], F115[3.30], F116[3.31], L119[3.34], W161[4.50], L165[4.54], A169[4.58], L172[4.61], V173[4.62] | |
6fk7_IC | -14.0 | L59[1.54], Y60[1.55], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] |
Opsin, Bovine 6fk8 | ||
6fk8_EC | -14.5 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.3 | I263[6.46], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34], I290[7.37], P291[7.38] | |
-13.0 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], L46[1.41], M183, I286[7.33], F293[7.40] | |
-12.9 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175 | |
-12.3 | V81[2.48], F85[2.52], F115[3.30], F116[3.31], L119[3.34], W161[4.50], L165[4.54], A169[4.58], L172[4.61], V173[4.62] | |
6fk8_IC | -14.0 | L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60], W265[6.48], L266[6.49] |
-13.8 | L59[1.54], T62[1.57], V63[1.58], R69, L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] | |
-12.7 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
Opsin, Bovine 6fk9 | ||
6fk9_EC | -14.4 | F88[2.55], G89[2.56], T92[2.59], T93[2.60], F103, F105, G109[3.24], C110[3.25], L112[3.27], E113[3.28] |
-13.7 | W35[1.30], Q36[1.31], M39[1.34], Y43[1.38], L46[1.41], L50[1.45], F293[7.40], F294[7.41], T297[7.44] | |
-13.6 | V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175 | |
-12.4 | F159[4.48], M163[4.52], W175, S202[5.37], I205[5.40], Y206[5.41], V209[5.44], V210[5.45] | |
-12.2 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], V271[6.54], I286[7.33], F287[7.34], I290[7.37] | |
-12.2 | F85[2.52], F115[3.30], F116[3.31], L119[3.34], W161[4.50], L165[4.54], A169[4.58], L172[4.61], V173[4.62] | |
6fk9_IC | -13.7 | L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60], W265[6.48], L266[6.49] |
-13.7 | L59[1.54], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] | |
-12.9 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
Opsin, Bovine 6fka | ||
6fka_EC | -14.5 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.3 | W35[1.30], Q36[1.31], M39[1.34], Y43[1.38], L46[1.41], L50[1.45], F293[7.40], F294[7.41], T297[7.44] | |
-12.6 | A158[4.47], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-12.5 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-12.5 | V81[2.48], F85[2.52], F115[3.30], F116[3.31], L119[3.34], W161[4.50], L165[4.54], A169[4.58], L172[4.61], V173[4.62] | |
6fka_IC | -14.2 | L59[1.54], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] |
-13.9 | L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60], W265[6.48], L266[6.49] | |
Opsin, Bovine 6fkb | ||
6fkb_EC | -14.5 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.6 | W35[1.30], Q36[1.31], M39[1.34], Y43[1.38], L46[1.41], L50[1.45], F293[7.40], F294[7.41], T297[7.44] | |
-12.8 | F159[4.48], V162[4.51], M163[4.52], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175 | |
-12.3 | A158[4.47], W161[4.50], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-12.6 | F85[2.52], F115[3.30], L119[3.34], W161[4.50], L165[4.54], A169[4.58], L172[4.61], V173[4.62] | |
6fkb_IC | -13.1 | I133[3.48], Y136[3.51], P142, M163[4.52], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] |
Opsin, Bovine 6fkc | ||
6fkc_EC | -15.1 | I263[6.46], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F283, F287[7.34], M288[7.35], I290[7.37], P291[7.38] |
-14.3 | F88[2.55], G89[2.56], T92[2.59], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28] | |
-13.8 | W35[1.30], Q36[1.31], M39[1.34], Y43[1.38], L46[1.41], F293[7.40], F294[7.41], T297[7.44] | |
-12.7 | A158[4.47], W161[4.50], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
6fkc_IC | -14.0 | L59[1.54], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] |
Opsin, Bovine 6fkd | ||
6fkd_EC | -14.6 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.0 | Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], L46[1.41], M183, I286[7.33], F293[7.40] | |
-13.0 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], I286[7.33], F287[7.34], I290[7.37] | |
-13.0 | V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175 | |
6fkd_IC | -14.1 | F208[5.43], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], Q225[5.60], W265[6.48] |
-13.3 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
-13.7 | L59[1.54], T62[1.57], V63[1.58], R69, L77[2.44], V81[2.48], F85[2.52], W161[4.50] | |
Orexin receptor | ||
Orexin receptor Type 1, inactive, Human 4zjc | ||
4zjc_EC | -17.0 | K43, V48[1.34], L49[1.35], A52[1.38], A338[7.33], T341[7.36], F342[7.37], W345[7.40] |
-13.1 | I175[4.56], P178[4.59], W206, Y211[5.34], I214[5.37], Y215[5.38], C218[5.41], V222[5.45] | |
-12.7 | F220[5.43], Y224[5.47], L225[5.48], L228[5.51], A308[6.45], L312[6.49], V316[6.53], I319[6.56], L320[6.57], F324[6.61] | |
-12.4 | A117[3.23], K120[3.26], V121[3.27], Y124[3.30], A170[4.51], L173[4.54], A174[4.55], V177[4.58], A180[4.61] | |
-12.1 | L309[6.46], L312[6.49], P313[6.50], V316[6.53], L317[6.54], C339[7.34], F342[7.37], L346[7.41] | |
4zjc_IC | -14.0 | A51[1.37], V54[1.40], A55[1.41], V58[1.44], V59[1.45], I356[7.51], N359[7.54], F360[7.55] |
-12.8 | N87[2.45], L90[2.48], L94[2.52], L125[3.31], R162[4.43], I165[4.46], L166[4.47], W169[4.50] | |
-12.6 | K298[6.35], V302[6.39], V306[6.43], L309[6.46], F342[7.37], L346[7.41], I356[7.51], I357[7.52], F360[7.55], L361[7.56] | |
-13.1 | F57[1.43], L61[1.47], V62[1.48], T65[1.51], L66[1.52], L69[1.55], A97[2.55], A372[8.57], F373[8.58] | |
Orexin receptor Type 2, inactive, Human 4s0v | ||
4s0v_EC | -14.0 | Y53[1.31], V56[1.34], L57[1.35], G60[1.38], I63[1.41], A344[7.33], F348[7.37], W351[7.40] |
-13.3 | S125[3.23], K128[3.26], V129[3.27], Y132[3.30], I178[4.51], C181[4.54], I182[4.55], I185[4.58], A188[4.61] | |
-12.8 | V179[4.52], I183[4.56], P186[4.59], W214, Y219[5.34], Y223[5.38], C226[5.41], V230[5.45] | |
-12.4 | I315[6.46], L318[6.49], P319[6.50], I322[6.53], L323[6.54], L326[6.57], F333, W345[7.34] | |
4s0v_IC | -13.7 | L98[2.48], Y132[3.30], L133[3.31], R170[4.43], I173[4.46], V174[4.47], W177[4.50], C181[4.54] |
-13.1 | F228[5.43], M233[5.48], L236[5.51], V240[5.55], M307[6.38], L310[6.41], L311[6.42], A314[6.45], I322[6.53] | |
Orexin receptor Type 2, inactive, Human 5wqc | ||
5wqc_EC | -13.9 | Y53[1.31], V56[1.34], L57[1.35], G60[1.38], I63[1.41], A344[7.33], F348[7.37], W351[7.40] |
-13.4 | S125[3.23], K128[3.26], V129[3.27], Y132[3.30], I178[4.51], C181[4.54], I182[4.55], I185[4.58] | |
-13.3 | V179[4.52], I183[4.56], P186[4.59], W214, Y219[5.34], P220[5.35], M222[5.37], Y223[5.38], C226[5.41] | |
-12.6 | Y53[1.31], V56[1.34], L57[1.35], Y343[7.32], A344[7.33], W345[7.34], T347[7.36], F348[7.37], W351[7.40] | |
5wqc_IC | -13.7 | I62[1.40], I63[1.41], V66[1.44], V67[1.45], I362[7.51], N365[7.54], F375[8.54], F379[8.58] |
-12.9 | L143[3.41], C147[3.45], L150[3.48], S172[4.45], I175[4.48], V179[4.52], I183[4.56], V230[5.45] | |
-12.9 | M233[5.48], L236[5.51], V240[5.55], Y243[5.58], M307[6.38], L310[6.41], L311[6.42], A314[6.45], I322[6.53] | |
-12.9 | F65[1.43], L69[1.47], I70[1.48], V73[1.51], L74[1.52], A378[8.57], F379[8.58], C382 | |
-13.5 | L98[2.48], Y132[3.30], L133[3.31], R170[4.43], I173[4.46], V174[4.47], W177[4.50], C181[4.54] | |
-12.8 | G60[1.38], I63[1.41], V64[1.42], V312[6.43], W351[7.40], A359[7.48], I362[7.51], I363[7.52], F366[7.55], L367[7.56] | |
Orexin receptor Type 2, inactive, Human 5ws3 | ||
5ws3_EC | -13.7 | Y53[1.31], V56[1.34], L57[1.35], G60[1.38], I63[1.41], A344[7.33], F348[7.37], W351[7.40] |
-13.5 | Q124[3.22], S125[3.23], K128[3.26], V129[3.27], Y132[3.30], I178[4.51], C181[4.54], I182[4.55], I185[4.58], A188[4.61] | |
-12.6 | L143[3.41], V179[4.52], I183[4.56], P186[4.59], W214, Y219[5.34], Y223[5.38], C226[5.41], V230[5.45] | |
5ws3_IC | -14.8 | Y132[3.30], R170[4.43], V174[4.47], W177[4.50], I178[4.51], C181[4.54], I182[4.55], I185[4.58] |
-14.4 | L236[5.51], M239[5.54], V240[5.55], Y243[5.58], L244[5.59], L310[6.41], L311[6.42], A314[6.45], I315[6.46], L318[6.49] | |
-13.6 | L69[1.47], I70[1.48], V73[1.51], L74[1.52], A378[8.57], F379[8.58], C381, C382 | |
-15.0 | I62[1.40], V66[1.44], V67[1.45], I70[1.48], I362[7.51], N365[7.54], F375[8.54], F379[8.58] | |
-12.7 | L143[3.41], C147[3.45], L150[3.48], I175[4.48], V179[4.52], I183[4.56], C226[5.41], V230[5.45] | |
-12.5 | G60[1.38], I63[1.41], V64[1.42], V308[6.39], V312[6.43], W351[7.40], A359[7.48], I362[7.51], I363[7.52], F366[7.55], L367[7.56] | |
-13.3 | N95[2.45], L98[2.48], L102[2.52], T106[2.56], V129[3.27], L133[3.31], I173[4.46], W177[4.50] | |
P2Y receptor | ||
P2Y1 receptor, inactive, with cholesterol, Human 4xnv | ||
4xnv_EC | -12.9 | I178[4.52], V181[4.55], A182[4.56], P185[4.59], Y189[4.63], Y217[5.38], C220[5.41], A224[5.45] |
-12.7 | I59[1.40], F62[1.43], I63[1.44], L67[1.48], P105[2.58], I108[2.61], F109[2.62], F112[2.65] | |
-12.2 | F215[5.36], M219[5.40], F226[5.47], C227[5.48], L230[5.51], L234[5.55], I274[6.49], V278[6.53], T281[6.56], R285[6.60] | |
-12.5 | G48, F49[1.30], Y52[1.33], Y53[1.34], A56[1.37], V57[1.38], L60[1.41], L315[7.44], V319[7.48] | |
-12.1 | A270[6.45], I274[6.49], P275[6.50], V278[6.53], M279[6.54], M282[6.57], V302[7.31], T305[7.34] | |
4xnv_IC | -13.5 | W83, V88[2.41], F91[2.44], N92[2.45], L95[2.48], I169[4.43], S172[4.46], V173[4.47], W176[4.50], V180[4.54] |
-13.0 | Y89[2.42], L140[3.41], C144[3.45], A147[3.48], H148[3.49], I171[4.45], V175[4.49], I178[4.52], A224[5.45], M225[5.46], L232[5.53] | |
P2Y1 receptor, inactive, Human 4xnw | ||
4xnw_EC | -14.4 | I178[4.52], V181[4.55], A182[4.56], P185[4.59], Y189[4.63], S213[5.34], I216[5.37], Y217[5.38], C220[5.41] |
-13.6 | F215[5.36], M219[5.40], T222[5.43], F226[5.47], C227[5.48], L230[5.51], L234[5.55], I274[6.49], V278[6.53], T281[6.56], R285[6.60] | |
-13.1 | F215[5.36], M219[5.40], V223[5.44], C227[5.48], V228[5.49], V231[5.52], T281[6.56], R285[6.60] | |
-12.2 | F49[1.30], Y53[1.34], V57[1.38], V271[6.46], V308[7.37], L312[7.41], L315[7.44], V319[7.48] | |
-11.8 | I59[1.40], F62[1.43], I63[1.44], L67[1.48], P105[2.58], I108[2.61], F109[2.62], F119 | |
-12.2 | T267[6.42], A270[6.45], V271[6.46], P275[6.50], A304[7.33], T305[7.34], V308[7.37], T309[7.38], L312[7.41] | |
4xnw_IC | -13.7 | W83, V88[2.41], F91[2.44], N92[2.45], L95[2.48], F129[3.30], K165[4.39], I169[4.43], V173[4.47], W176[4.50], V180[4.54] |
-13.0 | V61[1.42], Y260[6.35], I264[6.39], L315[7.44], C318[7.47], V319[7.48], I322[7.51], L326[7.55] | |
-12.9 | Y89[2.42], L140[3.41], C144[3.45], A147[3.48], R162, I171[4.45], I178[4.52], A182[4.56], A224[5.45], M225[5.46] | |
P2Y12 receptor, inactive, with cholesterol, Human 4ntj | ||
4ntj_EC | -14.6 | Y192[5.41], Q195[5.44], V196[5.45], W199[5.48], L203[5.52], R256[6.55], T260[6.59], L261[6.60] |
-14.5 | F36[1.43], L40[1.47], L75[2.55], P78[2.58], F79[2.59], L82[2.62], R93[3.21], V96[3.24] | |
-13.8 | F246[6.45], I247[6.46], V250[6.49], P251[6.50], F254[6.53], A255[6.54], P258[6.57], Y259[6.58], V279[7.34] | |
-13.0 | I247[6.46], T275[7.30], Y278[7.33], V279[7.34], S282[7.37], T283[7.38], W285[7.40], L286[7.41], L289[7.44] | |
-12.8 | Q25[1.32], V26[1.33], P29[1.36], L30[1.37], T33[1.40], F37[1.44], I81[2.61], A85[2.65], L87 | |
4ntj_IC | -14.4 | N235[6.34], V236[6.35], F239[6.38], I242[6.41], A243[6.42], F246[6.45], I247[6.46], V250[6.49], P251[6.50] |
-13.8 | I61[2.41], N65[2.45], I68[2.48], L72[2.52], F106[3.34], K142[4.43], V146[4.47], W149[4.50], F153[4.54], M160[4.61] | |
-12.9 | I120[3.48], Y123[3.51], Q124[3.52], I200[5.49], L203[5.52], I204[5.53], V207[5.56], C208[5.57] | |
-13.0 | L117[3.45], I120[3.48], Q124[3.52], L144[4.45], F151[4.52], I193[5.42], V196[5.45], I197[5.46], I200[5.49] | |
P2Y1 receptor, inactive, with cholesterol, Human 4pxz | ||
4pxz_EC | -12.5 | I23[1.30], I247[6.46], P251[6.50], Y278[7.33], V279[7.34], S282[7.37], T283[7.38], L286[7.41] |
-12.4 | F95[3.23], Q98[3.26], V99[3.27], I103[3.31], L157[4.58], M160[4.61], I161[4.62], N164 | |
-12.3 | F246[6.45], V250[6.49], P251[6.50], F254[6.53], A255[6.54], P258[6.57], T275[7.30], L276[7.31], V279[7.34] | |
4pxz_IC | -13.9 | I61[2.41], N65[2.45], I68[2.48], L72[2.52], I103[3.31], F106[3.34], K142[4.43], V146[4.47], W149[4.50], F153[4.54], M160[4.61] |
-12.1 | L31[1.38], V34[1.41], I240[6.39], W285[7.40], L289[7.44], L293[7.48], F296[7.51], F300[7.55] | |
-11.9 | L117[3.45], I120[3.48], L144[4.45], Y192[5.41], I193[5.42], V196[5.45], I197[5.46], I200[5.49], I204[5.53] | |
P2Y1 receptor, inactive, Human 4py0 | ||
4py0_EC | -12.2 | V250[6.49], P251[6.50], F254[6.53], A255[6.54], P258[6.57], F268, T275[7.30], L276[7.31], V279[7.34] |
-12.0 | F246[6.45], I247[6.46], P251[6.50], T275[7.30], Y278[7.33], V279[7.34], S282[7.37], L286[7.41] | |
4py0_IC | -13.5 | I68[2.48], L72[2.52], I103[3.31], F106[3.34], K142[4.43], V146[4.47], W149[4.50], F153[4.54], M160[4.61] |
-12.5 | W199[5.48], F202[5.51], I206[5.55], Y209[5.58], T210[5.59], I242[6.41], F246[6.45], F254[6.53] | |
-12.4 | L117[3.45], I120[3.48], L144[4.45], V147[4.48], F151[4.52], Y192[5.41], I193[5.42], V196[5.45], I197[5.46], I200[5.49], I204[5.53] | |
-11.9 | L31[1.38], I240[6.39], I247[6.46], W285[7.40], L289[7.44], L293[7.48], F296[7.51], F300[7.55] | |
Rhodospin active state | ||
Rhodopsin activate state, Bovine 2x72 | ||
2x72_EC | -14.5 | F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], Q113[3.28] |
-13.4 | Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], L46[1.41], M183, I286[7.33], T289[7.36], F293[7.40] | |
-12.8 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-13.0 | F159[4.48], V162[4.51], M163[4.52], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
2x72_IC | -14.2 | L59[1.54], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], L119[3.34], W161[4.50] |
-13.3 | I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60], L266[6.49] | |
-12.7 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
-13.0 | F56[1.51], L59[1.54], Y60[1.55], V63[1.58], Q64[1.59], L84[2.51], F85[2.52], F88[2.55] | |
Rhodopsin activate state, MII, Bovine 3pqr | ||
3pqr_EC | -14.4 | V81[2.48], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.0 | Q36[1.31], F37[1.32], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], F293[7.40] | |
-12.4 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], V271[6.54], F283, F287[7.34] | |
-12.4 | A158[4.47], W161[4.50], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-12.3 | F159[4.48], M163[4.52], A166[4.55], P170[4.59], V173[4.62], W175, Y206[5.41], V210[5.45] | |
-13.2 | L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], H278[6.61] | |
3pqr_IC | -12.9 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56] |
-12.8 | L59[1.54], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] | |
-12.6 | F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], L266[6.49] | |
Rhodopsin activate state, MII, Bovine 3pxo | ||
3pxo_EC | -14.4 | F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.6 | Q36[1.31], F37[1.32], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], F293[7.40] | |
-13.1 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-12.9 | L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], H278[6.61] | |
-12.7 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], V271[6.54], F283, F287[7.34] | |
3pxo_IC | -13.4 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] |
Rhodopsin activate state, MII, Bovine 4a4m | ||
4a4m_EC | -14.6 | V81[2.48], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28], F116[3.31] |
-13.3 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], T289[7.36], F293[7.40] | |
-13.2 | W175, S202[5.37], F203[5.38], I205[5.40], Y206[5.41], V209[5.44], V210[5.45], I214[5.49] | |
-13.0 | I48[1.43], M49[1.44], F52[1.47], F88[2.55], T92[2.59], T93[2.60], Y96[2.63], F105 | |
-12.9 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F283, F287[7.34] | |
-12.9 | F159[4.48], M163[4.52], A166[4.55], P170[4.59], V173[4.62], W175, Y206[5.41], V210[5.45] | |
4a4m_IC | -13.5 | F208[5.43], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60] |
-13.3 | L59[1.54], T62[1.57], V63[1.58], L77[2.44], V81[2.48], F85[2.52], F116[3.31], L119[3.34], W161[4.50] | |
-12.2 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56] | |
Rhodopsin activate state, Bovine4zwj | ||
4zwj_EC | -14.2 | L88[2.55], G89[2.56], S93[2.60], F103, F105, G109[3.24], C110[3.25], L112[3.27], Q113[3.28], F116[3.31] |
-13.8 | F159[4.48], V162[4.51], M163[4.52], L165[4.54], A166[4.55], A169[4.58], P170[4.59], A173[4.62], W175 | |
-13.8 | Q36[1.31], M39[1.34], L183, I286[7.33], T289[7.36], I290[7.37], F293[7.40], F294[7.41] | |
4zwj_IC | -14.0 | F208[5.43], F212[5.47], T213[5.48], M216[5.51], I217[5.52], F220[5.55], F221[5.56], Q225[5.60] |
-12.7 | F45[1.40], I48[1.43], V49[1.44], F52[1.47], P53[1.48], F56[1.51], L57[1.52], Y60[1.55], T320[8.57] | |
Rhodopsin activate state, with arrestin, Human 5dys | ||
5dys_EC | -14.4 | F88[2.55], G89[2.56], T93[2.60], F103, F105, G109[3.24], L112[3.27], E113[3.28] |
-12.8 | I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F283, F287[7.34] | |
5dys_IC | - | - |
Rhodopsin activate state, with arrestin, Human 5w0p | ||
5w0p_EC | -12.8 | I259[6.42], L262[6.45], I263[6.46], V266[6.49], P267[6.50], S270[6.53], V271[6.54], Y274[6.57], F287[7.34] |
-12.7 | A158[4.47], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], A173[4.62], W175 | |
-12.5 | L88[2.55], G89[2.56], S93[2.60], F105, G109[3.24], L112[3.27], Q113[3.28], F116[3.31] | |
5w0p_IC | -13.9 | F220[5.55], Y223[5.58], G224[5.59], V227[5.62], V254[6.37], I255[6.38], V258[6.41], L262[6.45] |
-13.1 | F45[1.40], I48[1.43], V49[1.44], F52[1.47], P53[1.48], F56[1.51], L57[1.52], Y60[1.55], T320[8.57] | |
-15.3 | F208[5.43], T213[5.48], M216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60] | |
Rhodospin inactive state | ||
Rhodospin inactive state, Bovine 1f88 | ||
1f88_EC | -15.5 | Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], T289[7.36], I290[7.37], F293[7.40], F294[7.41], T297[7.44] |
-13.4 | L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], T277[6.60], H278[6.61] | |
-12.9 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-12.7 | A158[4.47], W161[4.50], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62] | |
-13.5 | W175, E201[5.36], S202[5.37], F203[5.38], I205[5.40], Y206[5.41], V209[5.44], V210[5.45] | |
1f88_IC | -13.7 | T62[1.57], V63[1.58], K66, R69, Y74[2.41], L77[2.44], V157[4.46], W161[4.50], L165[4.54] |
-13.0 | Y43[1.38], I256[6.39], A260[6.43], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M309[7.56] | |
-12.8 | F220[5.55], Y223[5.58], E232[5.67], I259[6.42], L262[6.45], I263[6.46], L266[6.49], P267[6.50] | |
-13.0 | F212[5.47], I213[5.48], I217[5.52], F220[5.55], F221[5.56], G224[5.59], V227[5.62], L266[6.49] | |
-13.0 | W126[3.41], V129[3.44], I133[3.48], Y136[3.51], F159[4.48], M163[4.52], V210[5.45], I214[5.49], V218[5.53], C222[5.57] | |
Rhodospin inactive state, Bovine 1gzm | ||
1gzm_EC | -13.9 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], I290[7.37], F294[7.41], T297[7.44] |
-12.5 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-13.6 | F212[5.47], L216[5.51], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], H278[6.61] | |
-12.9 | I263[6.46], P267[6.50], V271[6.54], I286[7.33], F287[7.34], I290[7.37], P291[7.38], F294[7.41] | |
-13.2 | F85[2.52], T108[3.23], N111[3.26], L112[3.27], F115[3.30], F116[3.31], W161[4.50], L165[4.54] | |
-12.5 | W126[3.41], F159[4.48], M163[4.52], A166[4.55], W175, Y206[5.41], V210[5.45], I214[5.49] | |
-12.2 | A158[4.47], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-11.9 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T108[3.23], L112[3.27], F116[3.31] | |
-13.2 | W175, S202[5.37], I205[5.40], Y206[5.41], V209[5.44], V210[5.45], I214[5.49], I217[5.52] | |
1gzm_IC | -14.2 | R69, Y74[2.41], L77[2.44], N78[2.45], V81[2.48], F85[2.52], I154[4.43], V157[4.46], W161[4.50], L165[4.54] |
-12.8 | I133[3.48], V137[3.52], F146, F148, H152[4.41], M155[4.44], G156[4.45], F159[4.48], V162[4.51] | |
-13.0 | W126[3.41], V129[3.44], I133[3.48], Y136[3.51], F159[4.48], M163[4.52], V210[5.45], I214[5.49], V218[5.53], F221[5.56] | |
-12.2 | Y43[1.38], L47[1.42], I256[6.39], A260[6.43], T297[7.44], Y301[7.48], I305[7.52], M309[7.56] | |
Rhodospin inactive state, Bovine 1hzx | ||
1hzx_EC | -15.6 | Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], T289[7.36], I290[7.37], F293[7.40], F294[7.41], T297[7.44] |
-15.1 | F159[4.48], V162[4.51], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175, Y206[5.41] | |
-13.8 | F212[5.47], L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], T277[6.60], H278[6.61] | |
-13.6 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-12.8 | F45[1.40], I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], L95[2.62], Y96[2.63], F105 | |
-12.6 | F85[2.52], T108[3.23], N111[3.26], L112[3.27], F115[3.30], F116[3.31], W161[4.50], L165[4.54], L172[4.61] | |
1hzx_IC | -13.4 | Y74[2.41], L77[2.44], V81[2.48], F85[2.52], F116[3.31], I154[4.43], V157[4.46], W161[4.50] |
-13.1 | Y43[1.38], I256[6.39], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M308[7.55], M309[7.56] | |
-13.1 | F212[5.47], I213[5.48], I217[5.52], F220[5.55], F221[5.56], Y223[5.58], G224[5.59], V227[5.62] | |
-12.6 | I133[3.48], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
Rhodospin inactive state, Bovine 1l9h | ||
1l9h_EC | -14.5 | W35[1.30], Q36[1.31], M39[1.34], Y43[1.38], M183, I290[7.37], F294[7.41], T297[7.44] |
-12.6 | F85[2.52], T108[3.23], N111[3.26], L112[3.27], F115[3.30], F116[3.31], W161[4.50], L165[4.54], L172[4.61] | |
-13.0 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T92[2.59], F105, L112[3.27] | |
-12.6 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-14.4 | F212[5.47], L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], H278[6.61] | |
-13.9 | I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], L95[2.62], Y96[2.63], F105 | |
1l9h_IC | -13.4 | Y74[2.41], L77[2.44], V81[2.48], F85[2.52], F116[3.31], I154[4.43], V157[4.46], W161[4.50] |
-13.0 | Y43[1.38], I256[6.39], I263[6.46], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M308[7.55], M309[7.56] | |
-12.6 | W126[3.41], I133[3.48], F159[4.48], M163[4.52], Y206[5.41], V210[5.45], I214[5.49], V218[5.53], F221[5.56], C222[5.57] | |
Rhodospin inactive state, Bovine 1u19 | ||
1u19_EC | -14.5 | A32, Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], T289[7.36], I290[7.37], F293[7.40], F294[7.41], T297[7.44] |
-12.9 | F45[1.40], I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], L95[2.62], Y96[2.63], F105 | |
-12.8 | A158[4.47], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62], W175 | |
-13.0 | F56[1.51], F85[2.52], F88[2.55], G89[2.56], T92[2.59], T93[2.60], F105, L112[3.27] | |
-12.6 | F85[2.52], L112[3.27], F115[3.30], F116[3.31], L119[3.34], W161[4.50], L165[4.54], L172[4.61] | |
-12.4 | F212[5.47], L216[5.51], F220[5.55], L262[6.45], L266[6.49], F273[6.56], Y274[6.57], H278[6.61] | |
-13.1 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
1u19_IC | -13.5 | Y74[2.41], L77[2.44], V81[2.48], I154[4.43], V157[4.46], A158[4.47], W161[4.50], L165[4.54] |
-13.0 | Y43[1.38], I256[6.39], A260[6.43], I263[6.46], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M309[7.56] | |
-13.1 | F212[5.47], I213[5.48], I217[5.52], F220[5.55], F221[5.56], Y223[5.58], G224[5.59], L266[6.49] | |
Rhodospin inactive state, bathorhodopsin, Bovine 2g87 | ||
2g87_EC | -14.3 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], T289[7.36], I290[7.37], F293[7.40], F294[7.41], T297[7.44] |
-13.1 | F212[5.47], L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], T277[6.60], H278[6.61] | |
-12.7 | A158[4.47], W161[4.50], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62] | |
-12.6 | V81[2.48], F85[2.52], T108[3.23], N111[3.26], L112[3.27], F115[3.30], F116[3.31], W161[4.50], L165[4.54], L172[4.61] | |
-12.5 | F45[1.40], I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], L95[2.62], Y96[2.63], F105 | |
-12.4 | M163[4.52], A166[4.55], P170[4.59], V173[4.62], W175, Y206[5.41], V210[5.45], H211[5.46] | |
-13.5 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-12.8 | F56[1.51], L59[1.54], V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], L112[3.27] | |
2g87_IC | -12.9 | Y74[2.41], L77[2.44], V81[2.48], F115[3.30], I154[4.43], V157[4.46], W161[4.50], L165[4.54] |
-12.6 | Y43[1.38], I256[6.39], A260[6.43], I263[6.46], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M309[7.56] | |
Rhodospin inactive state, lumirhodopsin. Bovine 2hpy | ||
2hpy_EC | -14.1 | Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], T289[7.36], I290[7.37], F293[7.40], F294[7.41] |
-13.5 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], P170[4.59], V173[4.62], G174, W175 | |
-13.0 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-12.6 | I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], L95[2.62], Y96[2.63], F105 | |
-12.6 | V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], T93[2.60], F105, L112[3.27] | |
-12.3 | V81[2.48], F85[2.52], F115[3.30], F116[3.31], W161[4.50], L165[4.54], A169[4.58], L172[4.61], V173[4.62] | |
2hpy_IC | -13.5 | Y74[2.41], L77[2.44], N78[2.45], V81[2.48], F85[2.52], I154[4.43], V157[4.46], W161[4.50] |
-12.7 | Y43[1.38], I256[6.39], A260[6.43], I263[6.46], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M308[7.55], M309[7.56] | |
-12.6 | F212[5.47], I213[5.48], L216[5.51], I217[5.52], F220[5.55], F221[5.56], G224[5.59], L266[6.49] | |
Rhodospin inactive state, Bovine 2ped | ||
2ped_EC | -14.9 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], T289[7.36], I290[7.37], F293[7.40], F294[7.41], T297[7.44] |
-14.0 | F212[5.47], L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], T277[6.60], H278[6.61] | |
-13.1 | I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], L95[2.62], Y96[2.63], F105 | |
-14.1 | F159[4.48], V162[4.51], A166[4.55], A169[4.58], P170[4.59], V173[4.62], G174, W175 | |
-13.6 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-13.2 | I263[6.46], P267[6.50], V271[6.54], I286[7.33], F287[7.34], I290[7.37], P291[7.38], F294[7.41] | |
-12.5 | F85[2.52], T108[3.23], N111[3.26], L112[3.27], F115[3.30], F116[3.31], W161[4.50], L165[4.54], L172[4.61] | |
2ped_IC | -13.8 | F220[5.55], Y223[5.58], E232[5.67], R252[6.35], I255[6.38], I259[6.42], L262[6.45], L266[6.49] |
-13.2 | Y74[2.41], L77[2.44], V81[2.48], F85[2.52], I154[4.43], V157[4.46], A158[4.47], W161[4.50], L165[4.54] | |
-12.9 | F212[5.47], I213[5.48], I217[5.52], F220[5.55], F221[5.56], G224[5.59], Q225[5.60], L266[6.49] | |
-12.6 | Y43[1.38], I256[6.39], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M308[7.55], M309[7.56] | |
Rhodospin inactive state, Bovine 3c9l | ||
3c9l_EC | -14.2 | W35[1.30], Q36[1.31], M39[1.34], Y43[1.38], M183, I286[7.33], I290[7.37], T297[7.44] |
-13.0 | F85[2.52], T108[3.23], N111[3.26], L112[3.27], F115[3.30], F116[3.31], W161[4.50], L165[4.54] | |
-12.7 | L262[6.45], I263[6.46], L266[6.49], P267[6.50], G270[6.53], V271[6.54], Y274[6.57], F287[7.34] | |
-12.7 | F212[5.47], L216[5.51], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], H278[6.61] | |
-12.5 | A158[4.47], W161[4.50], V162[4.51], L165[4.54], A166[4.55], A169[4.58], P170[4.59], V173[4.62] | |
3c9l_IC | -13.8 | Y74[2.41], L77[2.44], N78[2.45], V81[2.48], F85[2.52], I154[4.43], V157[4.46], W161[4.50], L165[4.54] |
-12.8 | Y43[1.38], I256[6.39], A260[6.43], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M308[7.55], M309[7.56] | |
-12.9 | L59[1.54], V63[1.58], R69, L77[2.44], V81[2.48], L84[2.51], F85[2.52], F88[2.55] | |
Rhodospin inactive state, Bovine 3c9m | ||
3c9m_EC | -14.4 | Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], M183, I286[7.33], I290[7.37], F294[7.41] |
-12.9 | L262[6.45], I263[6.46], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], T277[6.60], H278[6.61] | |
3c9m_IC | -12.9 | Y43[1.38], I256[6.39], A260[6.43], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M308[7.55], M309[7.56] |
-12.8 | Y74[2.41], L77[2.44], V81[2.48], F85[2.52], I154[4.43], V157[4.46], A158[4.47], W161[4.50], L165[4.54] | |
-12.6 | I133[3.48], Y136[3.51], F159[4.48], M163[4.52], V210[5.45], I214[5.49], V218[5.53], F221[5.56] | |
Rhodospin inactive state, Bovine 3oax | ||
3oax_EC | -13.7 | W35[1.30], Q36[1.31], M39[1.34], L40[1.35], Y43[1.38], L46[1.41], M183, I286[7.33], I290[7.37] |
-13.1 | F159[4.48], V162[4.51], M163[4.52], A166[4.55], P170[4.59], V173[4.62], G174, W175, Y206[5.41] | |
-13.0 | F45[1.40], I48[1.43], M49[1.44], F52[1.47], P53[1.48], F88[2.55], T92[2.59], L95[2.62], Y96[2.63], F105 | |
-12.7 | I263[6.46], L266[6.49], P267[6.50], V271[6.54], I286[7.33], F287[7.34], I290[7.37], P291[7.38] | |
-12.5 | F212[5.47], L216[5.51], F220[5.55], L262[6.45], L266[6.49], G270[6.53], F273[6.56], Y274[6.57], H278[6.61] | |
-12.5 | F85[2.52], T108[3.23], N111[3.26], L112[3.27], F115[3.30], F116[3.31], W161[4.50], L165[4.54], L172[4.61] | |
-12.9 | L59[1.54], V81[2.48], L84[2.51], F85[2.52], F88[2.55], G89[2.56], L112[3.27], F116[3.31] | |
3oax_IC | -13.4 | V63[1.58], Y74[2.41], L77[2.44], I154[4.43], V157[4.46], A158[4.47], W161[4.50], L165[4.54] |
-12.7 | Y43[1.38], I256[6.39], A260[6.43], I263[6.46], F294[7.41], T297[7.44], Y301[7.48], V304[7.51], I305[7.52], M308[7.55], M309[7.56] | |
Rhodospin inactive state, Squid 2z73 | ||
2z73_EC | -14.3 | L272[6.46], P276[6.50], V280[6.54], W291, T293[7.31], Y295[7.33], A296[7.34], P300[7.38], F303[7.41] |
-13.4 | F78[2.48], F81[2.51], T82[2.52], L85[2.55], V86[2.56], L91[2.61], F103, G104[3.21], A107[3.24], V110[3.27] | |
-13.2 | F210[5.48], I213[5.51], V279[6.53], L282[6.56], L283[6.57], F286[6.60], G287[6.61], P288 | |
-12.2 | F78[2.48], A106[3.23], K109[3.26], V110[3.27], F113[3.30], I114[3.31], W160[4.50], I171[4.61] | |
2z73_IC | -13.3 | I213[5.51], I216[5.54], F217[5.55], Y220[5.58], F221[5.59], V224[5.62], I264[6.38], L271[6.45], S275[6.49], V279[6.53] |
-13.0 | G53[1.51], I56[1.54], Y57[1.55], T60[1.58], K61[1.59], F78[2.48], F81[2.51], L85[2.55] | |
-13.5 | C49[1.47], G50[1.48], G53[1.51], I54[1.52], Y57[1.55], F81[2.51], L85[2.55], F89[2.59], P90[2.60], F330[8.58] | |
-12.7 | I131[3.48], N135[3.52], I206[5.44], L207[5.45], G211[5.49], L214[5.52], I215[5.53], F218[5.56], C219[5.57] | |
-12.5 | T60[1.58], M71[2.41], I74[2.44], F153[4.43], I156[4.46], I157[4.47], W160[4.50], L161[4.51], V164[4.54] | |
Rhodospin inactive state, Squid 3ayn | ||
3ayn_EC | -14.1 | L272[6.46], P276[6.50], V279[6.53], V280[6.54], L283[6.57], W291, T293[7.31], A296[7.34], P300[7.38] |
-14.0 | F210[5.48], I213[5.51], L271[6.45], V279[6.53], L282[6.56], L283[6.57], F286[6.60], G287[6.61], P288 | |
-13.3 | L272[6.46], P276[6.50], T293[7.31], Y295[7.33], A296[7.34], L299[7.37], P300[7.38], F303[7.41] | |
-12.6 | F78[2.48], F81[2.51], T82[2.52], L85[2.55], V86[2.56], P90[2.60], L91[2.61], F103, A107[3.24], V110[3.27] | |
3ayn_IC | -14.7 | I39[1.37], F40[1.38], I43[1.41], I47[1.45], W332, V333, L334, T335, C336 |
-14.0 | I39[1.37], I43[1.41], I46[1.44], I47[1.45], W332, V333, L334, T335, C336 | |
-13.4 | G45[1.43], I46[1.44], C49[1.47], G50[1.48], G53[1.51], Y57[1.55], F81[2.51], L85[2.55], F89[2.59], F330[8.58] | |
-13.3 | I213[5.51], I216[5.54], F217[5.55], Y220[5.58], F221[5.59], V224[5.62], L271[6.45], S275[6.49], V279[6.53] | |
-12.8 | I131[3.48], Y134[3.51], I206[5.44], L207[5.45], L214[5.52], I215[5.53], F218[5.56], C219[5.57] | |
Sphingosine 1-phosphate receptor (S1P1) receptor | ||
Sphingosine 1-phosphate receptor (S1P1), inactive, Human 3v2y | ||
3v2y_EC | -13.0 | K41, S44[1.31], T48[1.35], V51[1.38], F52[1.39], I55[1.42], R292[7.34], Y295[7.37] |
-11.8 | F133[3.41], I170[4.52], I173[4.55], L174[4.56], L177[4.59], W182, F205[5.42], L213[5.50] | |
3v2y_IC | -13.9 | L61[1.48], I64[1.51], F65[1.52], L68[1.55], I325[8.57], M326[8.58], G327[8.59], R328, L330 |
-13.0 | L67[1.54], I70[1.57], W71[1.58], Y82[2.41], L89[2.48], F161[4.43], I164[4.46], S165[4.47], W168[4.50], V169[4.51], L172[4.54] | |
-12.4 | I64[1.51], L67[1.54], I70[1.57], W71[1.58], Y82[2.41], L89[2.48], L92[2.51], L93[2.52], V96[2.55] | |
Thrombin receptor 1 (PAR1) | ||
Thrombin receptor 1 (PAR1), inactive, Human 3vw7 | ||
3vw7_EC | -13.1 | F319[6.41], I323[6.45], I324[6.46], P328[6.50], F351[7.33], A352[7.34], L355[7.37], C356[7.38] |
-13.1 | T110[1.40], F113[1.43], V114[1.44], P118[1.48], P156[2.58], I159[2.61], S160[2.62], F170 | |
-13.0 | A228[4.51], L229[4.52], A232[4.55], P236[4.59], K240[4.63], L263, Y267[5.35], Y270[5.38] | |
-12.7 | V149[2.51], L150[2.52], S153[2.55], V154[2.56], F157[2.59], E173[3.23], L174[3.24], F177[3.27] | |
-12.7 | F280[5.48], L283[5.51], F319[6.41], I323[6.45], P328[6.50], V331[6.53], L332[6.54], A352[7.34] | |
3vw7_IC | -13.5 | G111[1.41], V112[1.42], V115[1.45], L119[1.49], C365[7.47], P368[7.50], L369[7.51], Y372[7.54] |
-13.1 | V139[2.41], H143[2.45], L216[4.39], S220[4.43], C223[4.46], L224[4.47], W227[4.50], I231[4.54] | |
-13.0 | Y140[2.42], L191[3.41], T194[3.44], V195[3.45], I198[3.48], T222[4.45], L229[4.52], F274[5.42], V277[5.45], F278[5.46], P282[5.50], I285[5.53] | |
Viral GPCR Receptor (US28) | ||
Viral GPCR Receptor (US28), inactive, with cholesterol, 4xt1 | ||
4xt1_EC | -14.4 | A77[2.48], L80[2.51], L81[2.52], C84[2.55], L88[2.59], S101[3.22], V102[3.23], P103[3.24] |
-13.3 | I238[6.45], I239[6.46], L242[6.49], P243[6.50], L246[6.53], T247[6.54], S268[7.30], L269[7.31], R271[7.33], A272[7.34] | |
-12.6 | T105[3.26], L106[3.27], A109[3.30], V113[3.34], W152[4.50], V156[4.54], F163[4.61], M164[4.62] | |
-12.5 | L37[1.36], F38[1.37], G41[1.40], V42[1.41], L45[1.44], F46[1.45], M90[2.61], L94[2.65] | |
Run1.3 | -14.0 | I64, V70[2.41], I73[2.44], N74[2.45], A77[2.48], L81[2.52], C110[3.31], V113[3.34], C145[4.43], S148[4.46], I149[4.47], W152[4.50] |
Run1.11 | -13.1 | T123[3.44], L127[3.48], Y131[3.52], W151[4.49], F154[4.52], I158[4.56], I199[5.49], V203[5.53] |
Run1.14 | -12.8 | M193[5.43], F197[5.47], V198[5.48], L201[5.51], S202[5.52], S205[5.55], Y206[5.56], Y209[5.59], L246[6.53], F249[6.56] |
Viral GPCR Receptor (US28), inactive, with cholesterol, 4xt3 | ||
4xt3_EC | -12.8 | I238[6.45], I239[6.46], L242[6.49], P243[6.50], L246[6.53], T247[6.54], V250[6.57], F265[7.27], L269[7.31], A272[7.34] |
-12.5 | F154[4.52], I157[4.55], I158[4.56], I160[4.58], P161[4.59], V165, L180, Y184[5.34] | |
-12.7 | I239[6.46], F240[6.47], S268[7.30], R271[7.33], A272[7.34], L275[7.37], T276[7.38], L279[7.41] | |
-11.9 | L37[1.36], F38[1.37], G41[1.40], V42[1.41], L45[1.44], F46[1.45], M90[2.61], L94[2.65] | |
-12.5 | V35[1.34], F38[1.37], L39[1.38], V42[1.41], F46[1.45], R271[7.33], L275[7.37], L279[7.41], C282[7.44], L286[7.48] | |
Run1.2 | -14.0 | I64, V70[2.41], I73[2.44], N74[2.45], A77[2.48], L81[2.52], C110[3.31], C145[4.43], S148[4.46], I149[4.47], W152[4.50] |
Run1.11 | -13.3 | L127[3.48], Y131[3.52], F154[4.52], I158[4.56], E191[5.41], L194[5.44], I199[5.49], V203[5.53] |
Run1.14 | -13.2 | L127[3.48], Y130[3.51], Y131[3.52], L194[5.44], V198[5.48], I199[5.49], S202[5.52], V203[5.53] |
Run2.8 | -13.6 | E124[3.45], L127[3.48], R139, F147[4.45], F150[4.48], W151[4.49], F154[4.52], I157[4.55] |
Run2.17 | -12.8 | L201[5.51], S205[5.55], Y208[5.58], Y209[5.59], S212[5.62], I231[6.38], V234[6.41], L235[6.42], I238[6.45] |